Active Recombinant Human PDE7B (Active), GST-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | PDE7B-1532H Optional Service: Optional requirements on this protein |
Product Overview : | Full-length recombinant human PDE7B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
Description : | PDE7B is a cAMP-specific phosphodiesterase and a member of the cyclic nucleotide phosphodiesterase family that catalyzes the hydrolysis of cAMP to the corresponding 5-monophosphate and provides a mechanism to downregulate cAMP signaling. PDE7B is over-expressed in chronic lymphocytic leukemia and inhibition of PDE7B leads to induction of apoptosis. PDE7B has been identified as a candidate gene for measuring treatment response to risperidone and may confer susceptibility to schizophrenia. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 28 nmol/min/mg |
Molecular Mass : | ~73 kDa |
Protein length : | Full length |
Purity : | >80% |
Applications : | PDE Assay |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PDE7B phosphodiesterase 7B [ Homo sapiens ] |
Official Symbol : | PDE7B |
Synonyms : | PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3,5-cyclic phosphodiesterase; bA472E5.1; MGC88256; |
Gene ID : | 27115 |
mRNA Refseq : | NM_018945 |
Protein Refseq : | NP_061818 |
MIM : | 604645 |
UniProt ID : | Q9NP56 |
Chromosome Location : | 6q23-q24 |
Pathway : | G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; |
Function : | 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-nucleotide phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity; |
◆ Recombinant Protein
Pde7b-4752M | Recombinant Mouse Pde7b Protein, Myc/DDK-tagged | +Inquiry |
PDE7B-446H | Recombinant Human Phosphodiesterase 7B, GST-tagged | +Inquiry |
PDE7B-1607H | Recombinant Human PDE7B, His-tagged | +Inquiry |
PDE7B-30224TH | Recombinant Human PDE7B | +Inquiry |
PDE7B-30823TH | Recombinant Human PDE7B | +Inquiry |
|
◆ Lysates
PDE7B-3340HCL | Recombinant Human PDE7B 293 Cell Lysate | +Inquiry |
|
◆ Assay kits
Kit-1848 | PDE7B Assay Kit | +Inquiry |
|
Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy