Active Recombinant Human TGFBR2 protein, His-Avi-tagged, Biotinylated

• Cat.No.: TGFBR2-0796H
• Product Overview: Biotinylated Recombinant Human TGFBR2 protein(Thr23-Asp159), fused with His and Avi tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Human Latent TGFB1, His Tag at 1 μg/mL (100 μL/well) can bind Biotinylated Human TGF-beta RII, His,Avitag with a linear range of 5-78 ng/mL.Serial dilutions of Human TGF-beta RII, His Tag were added into Human Latent TGFB1, His Tag: Biotinylated Human TGF-beta RII, His,Avitag binding reactions. The half maximal inhibitory concentration (IC50) is 0.39287 μg/mL.
• Molecular Mass: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 19.1 kDa. The protein migrates as 28-40 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
• Proteinlength: Thr23-Asp159
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: TGFBR2 transforming growth factor, beta receptor II (70/80kDa) [ Homo sapiens ]
• Official Symbol: TGFBR2
• Synonyms: TGFBR2; transforming growth factor, beta receptor II (70/80kDa); MFS2, transforming growth factor, beta receptor II (70 80kD); TGF-beta receptor type-2; tbetaR-II; TGF-beta receptor type II; TGF-beta type II receptor; TGF-beta receptor type IIB; transforming growth factor-beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
• Gene ID: 7048
• mRNA Refseq: NM_001024847
• Protein Refseq: NP_001020018
• MIM: 190182
• UniProt ID: P37173