Active Recombinant Mouse Ccl12 Protein

• Cat.No.: Ccl12-001M
• Product Overview: Purified recombinant protein of Mouse MCP-5 (Ccl12) without tag was expressed in E.coli.

Specification

• Description: Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
• Source: E. coli
• Species: Mouse
• Bio-activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-50.0 ng/ml.
• Molecular Mass: 9.3 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Purity: >95%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Storage: Store at -80 centigrade.
• Storage Buffer: Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
• Reconstitution: Resuspend the protein in the desired concentration in proper buffer.

Gene Information

• Gene Name: Ccl12 chemokine (C-C motif) ligand 12 [ Mus musculus (house mouse) ]
• Official Symbol: Ccl12
• Synonyms: Ccl12; chemokine (C-C motif) ligand 12; MCP-5; Scya12; C-C motif chemokine 12; MCP-1-related chemokine; monocyte chemoattractant protein 5; monocyte chemotactic protein 5; small-inducible cytokine A12
• Gene ID: 20293
• mRNA Refseq: NM_011331
• Protein Refseq: NP_035461
• UniProt ID: Q62401