Active Recombinant Mouse CDH5, Fc Chimera

• Cat.No.: CDH5-148M
• Product Overview: Recombinant Mouse CDH5 (Accession # 2208309A) Asp46 - Gln592 was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Fc
• Protein Length: 46-592 a.a.
• Predicted N Terminal: Asp46
• Form: Lyophilized from a 0.2 µm filtered solution in Tris-Citrate.
• Bio-activity: Measured by its ability to inhibit proliferation of LL/2 mouse Lewis lung carcinoma cells. Immobilized rmVE-Cadherin/Fc inhibits LL/2 cell growth by 35 - 50%. The ED50 for this effect is typically 1.5 - 6.0 µg/mL.
• Molecular Mass: Recombinant Mouse CDH5, Fc Chimera has a calculated MW of 88.7 kDa (monomer). In SDS-PAGE migrates as 100-120 kDa, reducing conditions.
• Purity: >80%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Cdh5 cadherin 5 [ Mus musculus ]
• Official Symbol: CDH5
• Synonyms: CDH5; cadherin 5; cadherin-5; VE-cadherin; 7B4/cadherin-5; vascular endothelial cadherin; 7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225
• Gene ID: 12562
• mRNA Refseq: NM_009868
• Protein Refseq: NP_033998