Active Recombinant Mouse FCGRT&B2M protein, His-tagged, Low Endotoxin

• Cat.No.: FCGRT & B2M-1421M
• Product Overview: Recombinant Mouse FCGRT&B2M protein(Q61559(FCGRT) & P01887(B2M))(22-297 aa(FCGRT) & 21-119 aa(B2M)), fused with C-terminal His tag, was expressed in HEK293.

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Protein Length: 22-297 aa(FCGRT) & 21-119 aa(B2M)
• Form: Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Bio-activity: Loaded Mouse FcRn, His Tag on Anti-His-Biosensor can bind Trastuzumab, hFc Tag with an affinity constant of 40.00 nM as determined in BLI assay.
• Molecular Mass: The protein has a predicted MW of 32.1 kDa (FCGRT)&11.7 kDa (B2M). Due to glycosylation, the protein migrates to 50-55 kDa (FCGRT)&14-15 kDa (B2M) based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.01 EU per μg by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
• Reconstitution: Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: Fcgrt Fc receptor, IgG, alpha chain transporter [ Mus musculus ]
• Official Symbol: FCGRT
• Synonyms: FCGRT; Fc receptor, IgG, alpha chain transporter; IgG receptor FcRn large subunit p51; neonatal Fc receptor; igG Fc fragment receptor transporter alpha chain; FcRn
• Gene ID: 14132
• mRNA Refseq: NM_010189
• Protein Refseq: NP_034319
• Gene Name 2: B2m beta-2 microglobulin [ Mus musculus ]
• Official Symbol 2: B2m
• Synonyms 2: B2M; beta-2 microglobulin; beta-2-microglobulin; Ly-m11; beta2m; beta2-m
• Gene ID 2: 12010
• mRNA Refseq 2: NM_009735
• Protein Refseq 2: NP_033865