Active Recombinant Mouse Folr2 Protein, His tagged

• Cat.No.: Folr2-32M
• Product Overview: Recombinant Mouse Folr2 Protein (Met-Ser227) with a C-terminal 6-His tag was expressed in Mouse myeloma cell line. N-terminal Sequence Analysis: Arg21

Specification

• Species: Mouse
• Source: NS0
• Tag: His
• Protein Length: 1-227 aa
• Description: This gene encodes a receptor protein located on the plasma membrane that mediates folate uptake by cells. Mice lacking the product of this gene show no defects in embryonic development and grow normally into fertile adults. However, such mice were found to be highly susceptible to the teratogenic effects of arsenic. Alternate splicing of this gene results in multiple transcript variants.
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind Folic Acid-Bovine Serum Albumin with an estimated Kd < 1.6 nM.
• Molecular Mass: 25.1 kDa
• Endotoxin: <0.01 EU/μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
• Applications: Bioactivity
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 100 μg/mL in PBS.

Gene Information

• Gene Name: Folr2 folate receptor 2 (fetal) [ Mus musculus ]
• Official Symbol: Folr2
• Synonyms: FOLR2; folate receptor 2 (fetal); folate receptor beta; FR-beta; folate binding protein 2; folate-binding protein 2; FBP2; FR-P3; Folbp2; Folbp-2
• Gene ID: 14276
• mRNA Refseq: NM_008035
• Protein Refseq: NP_032061
• UniProt ID: Q05685