Active Recombinant Mouse Grem2

• Cat.No.: Grem2-666M
• Product Overview: Recombinant Mouse Grem2 (Accession # NP_035955) Arg22-Gln168, fused with an N-terminal Met, was produced in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Protein Length: Arg22-Gln168
• Predicted N Terminal: Met
• Form: Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
• Bio-activity: Measured by its ability to inhibit BMP-4-induced activity in MC3T3-E1 mouse preosteoblast cells.The ED50 for this effect is typically 0.03 - 0.12 µg/mL in the presence of 50 ng/mL of rhBMP-4.
• Molecular Mass: Recombinant Mouse Grem2, Met-tagged has a calculated MW of 17.1 kDa (monomer).
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Grem2 gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis) [ Mus musculus ]
• Official Symbol: Grem2
• Synonyms: GREM2; gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis); gremlin-2; Gremlin1; protein related to DAN and cerberus; cysteine knot superfamily 1, BMP antagonist 2; Prdc; Gremlin2
• Gene ID: 23893
• mRNA Refseq: NM_011825
• Protein Refseq: NP_035955