Active Recombinant Mouse Il23a Protein

Cat.No. : Il23a-3515M
Product Overview : Purified recombinant protein of Mouse interleukin 23, alpha subunit p19 (Il23a) without tag was expressed in Sf9.
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  • Gene Information
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Description : Low expression observed in reference dataset
Source : Sf9
Species : Mouse
Bio-activity : The ED50 is 0.5 - 0.8 ng/mL, corresponding to a specific activity of 1.25-2.0 × 10^6 units/mg, determined by mouse splenocytes IL-17A secretion induced by mIL-23 in a dose dependent manner. Under this assay, the bioactivity is equivalent
Molecular Mass : 55.4 kDa
Endotoxin : Less than 0.01 ng/μg protein as determined by the LAL method
Purity : > 95%, as determined by Coomassie stained SDS-PAGE.
Stability : Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Storage : Store at -80 centigrade.
Concentration : Protein formulated and vialed at >50 μg/mL in specified buffer
Storage Buffer : 1 x PBS
Gene Name : Il23a interleukin 23, alpha subunit p19 [ Mus musculus (house mouse) ]
Official Symbol : Il23a
Synonyms : Il23a; interleukin 23, alpha subunit p19; p1; IL-; p19; IL-23; interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; IL-23p19; interleukin-23 subunit p19
Gene ID : 83430
mRNA Refseq : NM_031252
Protein Refseq : NP_112542
UniProt ID : Q9EQ14

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is this bioactive cyno IL-23 heterodimer (p19/p40) or just the cyno IL-23p19 subunit? 02/01/2023

Please inquiry our product manager with specific product.

Are there any FDA-approved drugs targeting IL23A? 12/22/2021

Yes, drugs like ustekinumab and risankizumab, which target IL23A, have been approved for certain autoimmune diseases.

Is IL23A involved in the regulation of adaptive or innate immunity? 08/23/2018

IL23A primarily plays a role in regulating the adaptive immune response.

How is IL23A linked to the pathogenesis of ankylosing spondylitis? 01/25/2018

IL23A is associated with the inflammation of the spine and joints seen in ankylosing spondylitis, making it a target for therapeutic intervention.

How does IL23A contribute to rheumatoid arthritis? 09/01/2017

In rheumatoid arthritis, IL23A is involved in the dysregulation of the immune system, leading to joint inflammation and damage.

How is IL23A involved in inflammatory bowel diseases like Crohn's disease? 07/03/2016

IL23A is implicated in the pathogenesis of Crohn's disease, contributing to chronic inflammation in the gastrointestinal tract.

Customer Reviews (3)

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Reviews
04/18/2020

    Coupled with the manufacturer's exceptional technical support and commitment to customer satisfaction, researchers can confidently utilize the IL23A protein in their studies, knowing that they have the necessary resources and assistance to succeed.

    12/02/2016

      Its remarkable attributes and consistent results make it an indispensable tool in various experimental applications.

      02/25/2016

        Highly recommended for its exceptional performance in ELISA, the IL23A protein is a top contender for researchers involved in protein electron microscopy structure analysis.

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