Active Recombinant Mouse Il5
Cat.No. : | Il5-121M |
Product Overview : | Recombinant Mouse Il5 was expressed in CHO Cells. |
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Species : | Mouse |
Source : | CHO |
Tag : | Non |
Description : | Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Murine IL-5 is homodimeric protein with molecular weight ranging from 25 to 40 kDa due to glycosylation. |
Form : | Lyophilized after extensive dialysis against PBS. |
Bio-activity : | ED50< 0.5="" ng/ml,="" measured="" in="" a="" cell="" proliferation="" assay="" using="" tf-1="" cells,="" corresponding="" to="" a="" specific="" activity="" of="">2×106 units/mg. |
Molecular Mass : | 25-40 kDa, observed by non-reducing SDS-PAGE. |
AA Sequence : | Met21-Gly133. |
Endotoxin : | < 0.2="" eu/μg,="" determined="" by="" lal=""> |
Purity : | >95% as analyzed by SDS-PAGE and HPLC. |
Storage : | Lyophilized recombinant protein remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Gene Name | Il5 interleukin 5 [ Mus musculus ] |
Official Symbol | Il5 |
Synonyms | IL5; interleukin 5; interleukin-5; TRF; BCGF-II; B-cell growth factor II; T-cell replacing factor; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor; Il-5; |
Gene ID | 16191 |
mRNA Refseq | NM_010558 |
Protein Refseq | NP_034688 |
UniProt ID | P04401 |
Pathway | Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; |
Function | cytokine activity; cytokine activity; growth factor activity; interleukin-5 receptor binding; |
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Not For Human Consumption!
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