Active Recombinant Rat Jag1 Protein (Ser32-Asp1067), C-6×His-tagged
Cat.No. : | Jag1-12R |
Product Overview : | Recombinant Rat Jag1 Protein (Ser32-Asp1067) with substitutions GGARN56-60AE and DR63-64TLVRPY and a C-terminal 6-His tag was expressed in Mouse myeloma cell line. |
- Specification
- Gene Information
- Related Products
Description : | Enables Notch binding activity and receptor ligand activity. Involved in several processes, including animal organ regeneration; inner ear auditory receptor cell differentiation; and positive regulation of cardiac epithelial to mesenchymal transition. Located in plasma membrane. Human ortholog(s) of this gene implicated in Alagille syndrome; congenital heart disease; multiple sclerosis; and tetralogy of Fallot. Orthologous to human JAG1 (jagged canonical Notch ligand 1). |
Source : | Mouse myeloma cell line |
Species : | Rat |
Tag : | C-6×His |
Bio-activity : | Measured by the ability of the immobilized protein to enhance BMP-2 induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.4-2.4 μg/mL. |
Molecular Mass : | Predicted Molecular Mass: 114 kDa SDS-PAGE: 134-160 kDa, reducing conditions |
Protein Length : | Ser32-Asp1067 |
N-terminal Sequence Analysis : | Ser32 |
Endotoxin : | <0.10 EU/μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining. |
Storage : | 12 months from date of receipt, ≤ -20 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, ≤ -20 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
Reconstitution : | Reconstitute at 500 μg/mL in PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | Jag1 jagged canonical Notch ligand 1 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Jag1 |
Synonyms : | Jag1; jagged canonical Notch ligand 1; protein jagged-1; jagged 1 |
Gene ID : | 29146 |
mRNA Refseq : | NM_019147 |
Protein Refseq : | NP_062020 |
UniProt ID : | G3V710 |
Products Types
◆ Recombinant Protein | ||
JAG1-1226H | Recombinant Human JAG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Jag1-1264M | Recombinant Mouse Jag1 Protein, His-Sumo/MYC-tagged | +Inquiry |
JAG1-792H | Recombinant Human JAG1 Protein, MYC/DDK-tagged | +Inquiry |
Jag1-3625M | Recombinant Mouse Jag1 Protein, Myc/DDK-tagged | +Inquiry |
JAG1-2348H | Recombinant Human JAG1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
JAG1-2382HCL | Recombinant Human JAG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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