"PDCD4" Related Products

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Rabbit Anti-Human PDCD4 Polyclonal Antibody

Cat. No. : CPBT-56410RH
Product Overview : Rabbit Polyclonal antibody to Human PDCD4.
Antigen Description : This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Isotype : IgG
Immunogen : Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human PDCD4.
Host : Rabbit
Species : Human
Specificity : Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
Formulation : Liquid
Purity Detail : Immunogen affinity purified
Applications : ICC/IF, WB
Storage buffer : Preservative: 0.02% Sodium AzideConstituents: 1% BSA, PBS, pH 7.4
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence similarities : Belongs to the PDCD4 family.Contains 2 MI domains.
Gene Name : PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
Official Symbol : PDCD4
Synonyms : PDCD4; H731; MGC33046; MGC33047; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein; Nuclear antigen H731-like
Gene ID : 27250
mRNA Refseq : NM_014456
Protein Refseq : NP_055271
MIM : 608610
UniProt ID : Q53EL6
Chromosome Location : 10q24
Pathway : mTOR signaling pathway
Function : RNA binding; binding; protein binding

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