"IL17A" Related Products

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Recombinant Equine Interleukin 17A

Cat. No.: IL17A-254E
Product Overview: Recombinant Equine IL-17A was expressed inYeast. MW= 14.9 kDa (130 aa).
Description: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Source: Yeast.
Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification: Ion-exchange chromatography.
Purity: >95% as visualized by SDS-PAGE analysis.
Amino Acid Sequence: GIVIPQNPEC PNTGDKNFPQ NVKINLNVLN RKTNSRRASD YHNRSTSPWN LHRNEDPERY PSVIWEAKCR HLGCVNAEGK VDFHMNSVPI QQEILVLRRE SQNCPHSFQL EKMLVAVGCT CVTPIVRHMG.
Bioactivity: In testing.
Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Gene Name: IL17A interleukin 17A [ Equus caballus ]
Synonyms: interleukin 17A; IL17A; IL17; interleukin 17
Gene ID: 100034142
mRNA Refseq: NM_001143792.1
Protein Refseq: NP_001137264.1
Chromosome Location: 20
Pathway: Cytokine-cytokine receptor interaction

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