Recombinant Bovine Interleukin 21
Cat.No. : | IL21-238B |
Product Overview : | Recombinant Bovine IL-21 was expressed inYeast. MW= 15.1 kDa (129 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL21-238B |
Description : | Interleukin-21 is a protein that in humans is encoded by the IL21 gene. Interleukin 21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells.This cytokine induces cell division/proliferation in its target cells. |
Source : | Yeast. |
Formulation/ Reconstitution : | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
Purification : | Ion-exchange chromatography. |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Amino Acid Sequence : | HKSSSQGQDR LFIRLRQLID IVDQLKNYVN DLDPEFLPAP EDVKRHCERS AFSCFQKVQL KSANNGDNEK IINILTKQLK RKLPATNTGR RQKHEVTCPS CDSYEKKPPK EYLERLKSLI QKMIHQHLS. |
Bioactivity : | In testing. |
Stability And Storage : | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
Gene Name : | IL21 interleukin 21 [ Bos taurus ] |
Synonyms : | interleukin 21; IL21; interleukin-21; IL-21 |
Gene ID : | 378475 |
mRNA Refseq : | NM_198832.1 |
Protein Refseq : | NP_942129.1 |
UniProt ID : | Q76LU5 |
Chromosome Location : | 17 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway |
Function : | cytokine activity; interleukin-2 receptor binding |
Products Types
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionIL21 has demonstrated efficacy in preclinical and clinical studies for various cancers, including melanoma, renal cell carcinoma, and lymphoma.
Common side effects may include fatigue, fever, and flu-like symptoms. However, the severity and type of side effects can vary among individuals.
IL21 is often investigated in combination with other cancer therapies to enhance its effectiveness, and it has shown promise in combination treatments.
Yes, several clinical trials are investigating the efficacy and safety of IL21 in autoimmune diseases, such as rheumatoid arthritis and lupus.
IL21 promotes the differentiation and survival of memory T cells, contributing to the long-term immune response against pathogens.
Customer Reviews (3)
Write a reviewWith the IL21 protein at hand, I am excited to embark on my scientific journey with confidence and optimism.
I am confident that incorporating the IL21 protein into my research will yield accurate and reliable results, enabling deeper insights into cellular processes
Their expertise and guidance will undoubtedly prove valuable in overcoming hurdles and maximizing the potential of this protein in my research endeavors.
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