| Cat. No.: | IL21-238B |
| Product Overview: | Recombinant Bovine IL-21 was expressed inYeast. MW= 15.1 kDa (129 aa). |
| Description: | Interleukin-21 is a protein that in humans is encoded by the IL21 gene. Interleukin 21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells.This cytokine induces cell division/proliferation in its target cells. |
| Source: | Yeast. |
| Formulation/ Reconstitution: | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
| Purification: | Ion-exchange chromatography. |
| Purity: | >95% as visualized by SDS-PAGE analysis. |
| Amino Acid Sequence: | HKSSSQGQDR LFIRLRQLID IVDQLKNYVN DLDPEFLPAP EDVKRHCERS AFSCFQKVQL KSANNGDNEK IINILTKQLK RKLPATNTGR RQKHEVTCPS CDSYEKKPPK EYLERLKSLI QKMIHQHLS. |
| Bioactivity: | In testing. |
| Stability And Storage: | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
| Gene Name: | IL21 interleukin 21 [ Bos taurus ] |
| Synonyms: | interleukin 21; IL21; interleukin-21; IL-21 |
| Gene ID: | 378475 |
| mRNA Refseq: | NM_198832.1 |
| Protein Refseq: | NP_942129.1 |
| UniProt ID: | Q76LU5 |
| Chromosome Location: | 17 |
| Pathway: | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway |
| Function: | cytokine activity; interleukin-2 receptor binding |
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