"LTA" Related Products

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Recombinant Human Lymphotoxin Alpha (TNF superfamily, member 2), His-tagged

Cat. No.: LTA-5068H
roduct Overview: Recombinant LTAprotein was expressed in E. coli and purified by using conventionalchromatography techniques.
Description: LTA, a member of thetumor necrosis factor family, is a cytokine produced by lymphocytes. Theprotein is highly inducible, secreted, and forms heterotrimers withlymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. Thisprotein also mediates a large variety of inflammatory, immunostimulatory, andantiviral responses, is involved in the formation of secondary lymphoidorgans during development and plays a role in apoptosis.
Concentration: 0.5 mg/ml
Source: Human
Host: E. coli
Form: Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 30% glycerol, 0.1MNaCl, and 1mM DTT.
Purity: > 90% by SDS -PAGE
Sequence: 35-205 amino acids:MGSSHHHHHH SSGLVPRGSH MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANTDRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQKMVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL
Molecular Mass: 20.9 kDa(192aa), confirmed by MALDI-TOF.
Applications: SDS-PAGE
Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: LTA
Gene Name: LTAlymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
Synonyms: LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB;TNFSF1; lymphotoxin-alpha; LT-alpha; TNF-beta; OTTHUMP00000029184;OTTHUMP00000165897; tumor necrosis factor beta; tumor necrosis factor ligandsuperfamily member 1
Gene ID: 4049
mRNA Refseq: NM_000595
Protein Refseq: NP_000586
MIM: 153440
UniProt ID: P01374
Chromosome Location: 6p21.3
Pathway: Apoptosis;Cytokine-cytokine receptor interaction; HTLV-I infection; Herpes simplexinfection; IL2 signaling events mediated by STAT5; IL4-mediated signaling events;Type I diabetes mellitus
Function: cytokineactivity; receptor binding; tumor necrosis factor receptor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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