Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, His-tagged
Cat.No. : | PDGFRA-1147H |
Product Overview : | Recombinant Human PDGFRA, fusedwith a His-tag at N-terminus, was expressed in E. coli and purifed byconventional chromatography, after refolding of the isolated inclusion bodiesin a renaturation buffer. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PDGFRA-1147H |
Description : | PDGFRA, also knownas platelet derived growth factor receptor alpha, is a cell surface tyrosinekinase receptor for members of the platelet-derived growth factor family.This protein can bind to both A and B subunits of PDGF. It is particularlyimportant for kidney development since mice heterozygous for the receptorexhibit defective kidney phenotypes. |
Concentration : | 0.5 mg/ml |
Source : | Human |
Host : | E. coli |
Form : | Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1MNaCl and 1mM DTT. |
Purity : | > 85% by SDS-PAGE |
Sequence : | 24-524 amino acids:MGSSHHHHHH SSGLVPRGSH MQLSLPSILP NENEKVVQLN SSFSLRCFGE SEVSWQYPMS EEESSDVEIRNEENNSGLFV TVLEVSSASA AHTGLYTCYY NHTQTEENEL EGRHIYIYVP DPDVAFVPLG MTDYLVIVEDDDSAIIPCRT TDPETPVTLH NSEGVVPASY DSRQGFNGTF TVGPYICEAT VKGKKFQTIP FNVYALKATSELDL. |
Molecular Mass : | 58.4 kDa(522 aa) |
Applications : | SDS-PAGE |
Storage : | Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
OfficialSymbol : | PDGFRA |
Gene Name : | PDGFRA platelet-derived growthfactor receptor, alpha polypeptide [ Homo sapiens ] |
Synonyms : | PDGFRA;platelet-derived growth factor receptor, alpha polypeptide; CD140A;PDGFR2; MGC74795; RHEPDGFRA; Alpha-type platelet-derived growth factor receptor; PDGF-R-alpha; EC 2.7.10.1; CD140antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; rearranged-in-hypereosinophilia-platelet derived growth factorreceptor alpha fusion protein; PDGFRA/BCR fusion; OTTHUMP00000218653; OTTHUMP00000218654; OTTHUMP00000218655;OTTHUMP00000218656; OTTHUMP00000218657; OTTHUMP00000218658; OTTHUMP00000158882 |
Gene ID : | 5156 |
mRNA Refseq : | NM_006206 |
Protein Refseq : | NP_006197 |
MIM : | 173490 |
UniProt ID : | P16234 |
Chromosome Location : | 4q12 |
Pathway : | Calcium signaling pathway;Colorectal cancer; Cytokine-cytokine receptor interaction; Endocytosis; Focaladhesion; Gap junction; Glioma; Pathways in cancer; Regulation of actincytoskeleton; Signaling by PDGF |
Function : | ATP binding; nucleotidebinding; platelet-derived growth factor alpha-receptor activity;platelet-derived growth factor binding; platelet-derived growth factorreceptor binding; protein heterodimerization activity; receptor activity;transferase activity; vascular endothelial growth factor receptor activity |
Products Types
◆ Recombinant Protein | ||
PDGFRA-270H | Recombinant Human PDGFRA Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
PDGFRA-188H | Recombinant Human PDGFRA Protein, His-tagged | +Inquiry |
Pdgfra-4758M | Recombinant Mouse Pdgfra Protein, Myc/DDK-tagged | +Inquiry |
PDGFRA-1282R | Recombinant Rat PDGFRA protein(Met1-Glu523), hFc-tagged | +Inquiry |
PDGFRA-111H | Recombinant Human PDGFRA Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
PDGFRA-824RCL | Recombinant Rat PDGFRA cell lysate | +Inquiry |
PDGFRA-2657HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-001HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1615 | PDGFRa Functional Assay Kit | +Inquiry |
Kit-1616 | U2OS PDGFRa Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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