"NT5M" Related Products

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Recombinant Human 5',3'-Nucleotidase, Mitochondrial, His-tagged

Cat. No.: NT5M-1722H
Product Overview: Recombinant humanNT5M protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.
Description: NT5M, also known asDNT2, belongs to the 5"(3")-deoxyribonucleotidase family. It localizes to themitochondrial matrix. This enzyme dephosphorylates the 5"- and2"(3")-phosphates of uracil and thymine deoxyribonucleotides. The gene islocated on chromosome 17 p11.2 in the critical region deleted in theSmith-Magenis syndrome (SMS), a genetic disease of unknown etiology.
Source: Human
Concentration: 0.5 mg/ml
Host: E. coli
Form: Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, with 20% glycerol, 0.1 M NaCl and 1 mM DTT.
Purity: > 98% pure bySDS-PAGE
Sequence: 32-228 amino acids:MGSSHHHHHH SSGLVPRGSH MGGRALRVLV DMDGVLADFE GGFLRKFRAR FPDQPFIALE DRRGFWVSEQYGRLRPGLSE KAISIWESKN FFFELEPLPG AVEAVKEMAS LQNTDVFICT SPIKMFKYCP YEKYAWVEKYFGPDFLEQIV LTRDKTVVSA DLLIDDRPDI TGAEPTPSWE HVLFTACHNQ HLQLQPPRRR LHSWADDWKAILDS
Molecular Mass: 25.1 kDa
Applications: SDS-PAGE
Storage: Store at 4 deg C forshort term storage. Aliquot and store at -20 deg C or -70 deg C for long termstorage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: NT5M
nullValue_other: Q9NPB1
Gene Name: NT5M 5",3"-nucleotidase,mitochondrial [ Homo sapiens ]
Synonyms: NT5M;5",3"-nucleotidase, mitochondrial; mdN; dNT2; dNT-2;5"(3")-deoxyribonucleotidase, mitochondrial; OTTHUMP00000065515;deoxy-5"-nucleotidase 2; 5(3)-deoxyribonucleotidase; mitochondrial 5"nucleotidase; 5" nucleotidase, mitochondrial; EC 3.1.3.5
Gene ID: 56953
mRNA Refseq: NM_020201
Protein Refseq: NP_064586
MIM: 605292
Chromosome Location: 17p11.2
Pathway: Metabolic pathways;Metabolism of nucleotides; Nicotinate and nicotinamide metabolism; Purinemetabolism; Pyrimidine catabolism; Pyrimidine metabolism
Function: phosphataseactivity; nucleotide binding; nucleotidase activity; metal ion binding;hydrolase activity; 5"-nucleotidase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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