Recombinant Mouse Interleukin 2, His-tagged

• Cat.No.: ll2-538M
• Product Overview: Recombinant mouse ll2 protein wasexpressed in E. coli and purified by using conventional chromatographytechniques.

Specification

• Cat. No.: ll2-538M
• Description: ll2is an immunoregulatory lymphokine produced by T-cells in response toproteinic or mitogenic stimulation. ll2 signaling is required for T-cellproliferation and other fundamental functions which are essential for theimmune response. ll2 stimulates growth and differentiation of B-cells, NKcells, lymphokine activated killer cells, monocytes, macrophages andoligodendrocytes.
• Concentration: 0.5 mg/ml
• Source: Mouse
• Host: E. coli
• Form: Suppliedas a liquid in PBS, pH7.4, containing 20% glycerol, and 0.1M NaCl.
• Purity: > 95% by SDS -PAGE
• Sequence: 21-169 amino acids:MGSSHHHHHH SSGLVPRGSH MAPTSSSTSS STAEAQQQQQ QQQQQQQHLE QLLMDLQELL SRMENYRNLKLPRMLTFKFY LPKQATELKD LQCLEDELGP LRHVLDLTQS KSFQLEDAEN FISNIRVTVV KLKGSDNTFECQFDDESATV VDFLRRWIAF CQSVISTSPQ
• Molecular Mass: 19.5 kDa(170 aa), confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: Il2

Gene Information

• Gene Name: Il2interleukin 2 [ Mus musculus ]
• Synonyms: Il2;interleukin 2; Il-2; interleukin-2; OTTMUSP00000007837; TCGF;T-cell growth factor
• Gene ID: 16183
• mRNA Refseq: NM_008366
• Protein Refseq: NP_032392
• UniProt ID: P04351
• Chromosome Location: 3 B-C; 3 19.2 cM
• Pathway: Allograft rejection; Autoimmunethyroid disease; Cytokine-cytokine receptor interaction; Graft-versus-hostdisease; Jak-STAT signaling pathway; T cell receptor signaling pathway; TypeI diabetes mellitus
• Function: cytokine activity; growthfactor activity; interleukin-2 receptor binding; protein binding; kappa-typeopioid receptor binding; carbohydrate binding