"APOC3" Related Products


Native Human Apolipoprotein C-III

Cat. No. : APOC3-361H
Product Overview : Native human APOC3expressed by Human Plasma is a 8.76 kDa protein.
Description : APOC3inhibits the activation of lipoprotein lipase by Apo CII. Reduced levels of APOC3result in higher fatty acid uptake from plasma triglycerides into adiposetissue. Thus, APOC3 is a potential target for treatment of obesity andinsulin resistance. The normal plasma concentration of APOC3 is 8-15 mg per100 ml. Prepared from fresh, non-frozen plasma shown to be non reactive forHbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDAapproved tests. >95 percent pure by SDS-PAGE.
Source : Human Plasma
Species : Human
Form : Liquid in 0.01MAmmonium Bicarbonate; pH 7.4.
Molecular Weight : 8.76 kDa
Concentration : 1.0 mg/ml
Purity : >95 percent pure by SDS-PAGE
Storage : When stored at -80°Cproduct is stable for 3 years from date of delivery. Avoid repeatedfreeze-thaw cycles.
OfficialSymbol : APOC3
Gene Name : APOC3 apolipoprotein C-III [ Homosapiens ]
Synonyms : APOC3; apolipoproteinC-III; HALP2; APOCIII; MGC150353; apolipoproteinC-III; apo-CIII; apoC-III; apolipoprotein C3; OTTHUMP00000043270;OTTHUMP00000069353
Gene ID : 345
mRNA Refseq : NM_000040
Protein Refseq : NP_000031
MIM : 107720
UniProt ID : P02656
Chromosome Location : 11q23.1-q23.2
Pathway : Chylomicron-mediatedlipid transport; HDL-mediated lipid transport; Lipid digestion; Lipoproteinmetabolism; Metabolism of lipids and lipoproteins; PPAR signaling pathway;Statin Pathway
Function : cholesterol binding;enzyme regulator activity; high-density lipoprotein particle receptorbinding; lipase inhibitor activity; phospholipid binding

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