"APOC3" Related Products


Native Human Apolipoprotein C-III

Cat. No.: APOC3-361H
Product Overview: Native human APOC3expressed by Human Plasma is a 8.76 kDa protein.
Description: APOC3inhibits the activation of lipoprotein lipase by Apo CII. Reduced levels of APOC3result in higher fatty acid uptake from plasma triglycerides into adiposetissue. Thus, APOC3 is a potential target for treatment of obesity andinsulin resistance. The normal plasma concentration of APOC3 is 8-15 mg per100 ml. Prepared from fresh, non-frozen plasma shown to be non reactive forHbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDAapproved tests. >95 percent pure by SDS-PAGE.
Source: Human Plasma
Species: Human
Form: Liquid in 0.01MAmmonium Bicarbonate; pH 7.4.
Molecular Weight: 8.76 kDa
Concentration: 1.0 mg/ml
Purity: >95 percent pure by SDS-PAGE
Storage: When stored at -80°Cproduct is stable for 3 years from date of delivery. Avoid repeatedfreeze-thaw cycles.
OfficialSymbol: APOC3
Gene Name: APOC3 apolipoprotein C-III [ Homosapiens ]
Synonyms: APOC3; apolipoproteinC-III; HALP2; APOCIII; MGC150353; apolipoproteinC-III; apo-CIII; apoC-III; apolipoprotein C3; OTTHUMP00000043270;OTTHUMP00000069353
Gene ID: 345
mRNA Refseq: NM_000040
Protein Refseq: NP_000031
MIM: 107720
UniProt ID: P02656
Chromosome Location: 11q23.1-q23.2
Pathway: Chylomicron-mediatedlipid transport; HDL-mediated lipid transport; Lipid digestion; Lipoproteinmetabolism; Metabolism of lipids and lipoproteins; PPAR signaling pathway;Statin Pathway
Function: cholesterol binding;enzyme regulator activity; high-density lipoprotein particle receptorbinding; lipase inhibitor activity; phospholipid binding

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