Native Human Actin, Alpha, Cardiac Muscle 1

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Native Human Actin, Alpha, Cardiac Muscle 1

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Cat. No. : ACTC1-5294H
Product Overview : Native human ACTC1 wasexpressed in ACTC1 Human Heart.
Description : Theactin family is comprised of 3 main groups of actin isoforms, alpha, beta,and gamma. The ACTC1 are found in muscle tissues and are a major constituentof the contractile apparatus. The beta and gamma actins coexist in most celltypes as components of the cytoskeleton. Defects in this gene have beenassociated with idiopathic dilated cardiomyopathy (IDC) and familialhypertrophic cardiomyopathy (FHC).
Form : Lyophilized from asolution containing 20 mM Tris + 0.2 M NaCl + 1 mM ATP.
Source : Human Heart
Biological Activity : Sample testedpositive for Muscle Actin activity by Western blot.
Concentration : 1 mg/ml
Endotoxin Level : < 0.1 ng/µg ofprotein.
Reconstitution : Reconstitute withneutral buffer or deionized water.
Storage : Reconstitutedprotein is stable for 1 week at 2-4°C. For long term storage, aliquot and freezeat -20°C. Avoid repeated freeze-thaw cycles.
Pathways : Cardiacmuscle contraction; Dilated cardiomyopathy; Hypertrophic cardiomyopathy(HCM); Myometrial Relaxation and Contraction Pathways; Striated MuscleContraction
PDBrendering based on 1atn. :

Gene Name : ACTC1 actin, alpha, cardiac muscle1 [ Homo sapiens ]
Official Symbol : ACTC1
Synonyms : ACTC1; actin, alpha, cardiacmuscle 1; ACTC; ASD5; CMD1R; CMH11; LVNC4; actin, alpha cardiac muscle 1;OTTHUMP00000160081; alpha-cardiac actin; Alpha-cardiac actin
Gene ID : 70
mRNA Refseq : NM_005159
Protein Refseq : NP_005150
MIM : 102540
UniProt ID : P68032
Chromosome Location : 15q11-q14
Function : ATPbinding; ATPase activity; myosin binding; nucleotide binding

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