Native Human Coagulation Factor V (proaccelerin, labile factor)

• Cat.No.: F5-1176H
• Product Overview: Native Human F5 was expressedin Human Plasma.

Specification

• Cat. No.: F5-1176H
• Description: NativeHuman Factor Va prepared by activating purified F5 with thrombin and purifiedby immunoaffinity chromatography. This process results in cofactorpreparations which are free of both activation peptides and thrombin.
• Source: Human Plasma
• Form: Liquid in 50% glycerol(v/v), 5 mM CaCl2.
• SpecificActivity: Measured in a F5clotting assay.
• Concentration: 5.0 mg/ml
• Molecular Weight: 168 kDa
• Storage: Store in working aliquots at -20°C. Avoidrepeated freeze-thaw cycles.
• Pathways: Blood Clotting Cascade; Complementand Coaqulation Cascades; Formation of Fibrin Clot (Clotting Cascade);Hemostasis; Platelet degranulation; Response to elevated cytosolicCa2+
• Function: copperion binding; metal ion binding; protein binding

Gene Information

• Gene Name: F5coagulation factor V (proaccelerin, labile factor) [ Homo sapiens ]
• Official Symbol: F5
• Synonyms: F5; coagulation factor V (proaccelerin, labile factor); FVL;PCCF; OTTHUMP00000032547; OTTHUMP00000032548; Coagulation factor V; Activitiedprotein C cofactor; Proaccelerin, labile factor; Coagulation factor V heavychain; Coagulation factor V light chain; coagulation factor V; coagulation factor V jinjiang A2 domain; factor V Leiden
• Gene ID: 2153
• mRNA Refseq: NM_000130
• Protein Refseq: NP_000121
• MIM: 612309
• UniProt ID: P12259
• Chromosome Location: 1q23