"GADD45A" Related Products

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Recombinant Rhesus Macaque Growth Arrest And DNA-damage-inducible, Alpha

Cat. No.: GADD45A-5195R
Product Overview: RecombinantRhesus Macaque GADD45A is a single, non-glycosylated polypeptide chaincontaining 165 amino acids.
Description: GADD45Ais a member of the GADD45 family of proteins. It is ubiquitously expressed,and induced by DNA damage. Upon induction, GADD45A binds to PCNA, stimulatesDNA excision repair, and initiates G2 cell cycle arrest.
Source: Rhesus Macaque
Host: E. coli
Form: Lyophilized from a 0.2 um sterile filteredsolution of PBS, pH 7.4.
Purity: >95%by SDS-PAGE and HPLC analyses.
Sequence: MTLEEFSAGEQKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQAFCCENDINIL RVSNPGRLAE LLLLETDAGP AATEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVINLPER
Molecular Weight: 18.3 kDa
Endotoxin: <0.1 ng/μg of Protein
Reconstitution: Centrifugevial prior to opening. Add sterile distilled water or aqueousbuffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be dividedinto working aliquots and stored at -80°C. Further dilutions should bemade in appropriate buffered solutions.
Storage: The lyophilized protein is stable at2-4°C, but should be kept desiccated at -20°C for long term storage. Afterreconstitution, the protein is stable for 1 week at 2-4°C. For long termstorage, aliquot and freeze at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol: GADD45A
Pathways: Cell cycle; MAPKsignaling pathway; p53 signaling pathway
Gene Name: GADD45A growth arrest andDNA-damage-inducible, alpha [ Macaca mulatta ]
Synonyms: GADD45A; growtharrest and DNA-damage-inducible, alpha; ENSMMUP00000019436; ENSMMUP00000039965
Gene ID: 701054
mRNA Refseq: XM_001095413
Protein Refseq: XP_001095413
UniProt ID: F6W540
Chromosome Location: 1

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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