Species : |
Rhesus macaque |
Source : |
Rhesus Macaque |
Tag : |
Non |
Description : |
GADD45Ais a member of the GADD45 family of proteins. It is ubiquitously expressed,and induced by DNA damage. Upon induction, GADD45A binds to PCNA, stimulatesDNA excision repair, and initiates G2 cell cycle arrest. |
Form : |
Lyophilized from a 0.2 um sterile filteredsolution of PBS, pH 7.4. |
Purity : |
>95%by SDS-PAGE and HPLC analyses. |
Sequence : |
MTLEEFSAGEQKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQAFCCENDINIL RVSNPGRLAE LLLLETDAGP AATEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVINLPER |
Molecular Weight : |
18.3 kDa |
Endotoxin : |
<0.1 ng/μg of Protein |
Reconstitution : |
Centrifugevial prior to opening. Add sterile distilled water or aqueousbuffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be dividedinto working aliquots and stored at -80°C. Further dilutions should bemade in appropriate buffered solutions. |
Storage : |
The lyophilized protein is stable at2-4°C, but should be kept desiccated at -20°C for long term storage. Afterreconstitution, the protein is stable for 1 week at 2-4°C. For long termstorage, aliquot and freeze at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : |
GADD45A |
Pathways : |
Cell cycle; MAPKsignaling pathway; p53 signaling pathway |