Recombinant Pig Colony Stimulating Factor 2 (granulocyte-macrophage)

• Cat.No.: CSF2-374P
• Product Overview: RecombinantPig CSF2 was expressed in HEK293T cells.

Specification

• Cat. No.: CSF2-374P
• Description: CSF2 is a cytokinethat functions as a white blood cell growth factor. CSF2 stimulates stemcells to produce granulocytes (neutrophils, eosinophils, and basophils) andmonocytes. Monocytes exit the circulation and migrate into tissue, whereuponthey mature into macrophages. Thus, it is part of the immune/inflammatorycascade, by which activation of a small number of macrophages can rapidlylead to an increase in their numbers, a process crucial for fightinginfection.
• Form: TissueCulture Supernatant from HEK293T cells expressing recombinant Porcine CSF2- lyophilized.
• Application: ELISA; FunctionalAssays
• Buffer Solution: 1% Bovine SerumAlbumin.
• Storage: Prior toreconstitution store at +4°C. Store at -70°C. Storagein frost-free freezers is not recommended. This product should be storedundiluted. Avoid repeated freezing and thawing as this may denature theantibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.
• Pathways: Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway;Hematopoietic cell lineage; Jak-STAT signaling pathway; Natural killer cellmediated cytotoxicity; T cell receptor signaling pathway

Gene Information

• Gene Name: CSF2colony stimulating factor 2 (granulocyte-macrophage) [ Sus scrofa ]
• Official Symbol: CSF2
• Synonyms: CSF2; colonystimulating factor 2 (granulocyte-macrophage); GM-CSF; granulocyte-macrophagecolony-stimulating factor; CSF; colony-stimulating factor; Granulocyte-macrophagecolony-stimulating factor; Colony-stimulating factor
• Gene ID: 397208
• mRNA Refseq: NM_214118
• Protein Refseq: NP_999283
• UniProt ID: Q29118
• Chromosome Location: 2

Reviews

01/15/2022

The product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.

07/27/2021

The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.

05/19/2019

Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.

Q&As

How conserved is the sequence of CSF2 among different species?

The sequence of CSF2 is moderately conserved across different species.

What is the typical length of CSF2?

The length of CSF2 protein varies but is typically around 144 amino acids.

What is the main biological function of CSF2?

The primary function of CSF2 is to regulate the production and differentiation of white blood cells.

In what tissues or cells is CSF2 commonly expressed?

CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.

What does CSF2 stand for?

CSF2 stands for Colony Stimulating Factor 2.

Is CSF2 associated with any specific diseases or conditions?

CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.

Which cellular functions are associated with CSF2?

CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.