Native Mouse Vitronectin


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Native Mouse Vitronectin

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Cat. No. : Vtn-694M
Product Overview : Native mousemultimeric Vitronectin prepared from fresh mouse plasma using urea as adenaturant.
Description : The protein encodedby this gene is a member of the pexin family. Vitronectin is an abundantglycoprotein found in serum and the extracellular matrix and promotes celladhesion and spreading, inhibits the membrane-damaging effect of the terminalcytolytic complement pathway, and binds to several serpin serine proteaseinhibitors.
Source : Mouse plasma
Species : Mouse
Form : Liquid in 0.05 Msodium phosphate + 0.1 M NaCl, pH 7.4.
MolecularWeight : 75.0 kDa monomer
Concentration : 5.0 mg/ml
Storage : Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : Vtn
Pathways : ECM-receptorinteraction; Focal Adhesion; Focal adhesion; Inflammatory Response Pathway;Integrin cell surface interactions; Senescence and Autophagy; SignalTransduction
The SMB domain(yellow) in complex with PAI-1 :

Gene Name : Vtn vitronectin [ Musmusculus ]
Synonyms : Vtn; vitronectin;Vn; AI256434; S-protein; OTTMUSP00000000198; serum-spreading factor; Vitronectin; S-protein; Serum-spreading factor
Gene ID : 22370
mRNA Refseq : NM_011707
Protein Refseq : NP_035837
UniProt ID : P29788
Chromosome Location : 11 B5; 11 45.09 cM
Function : extracellular matrixbinding; heparin binding; integrin binding; polysaccharide binding; scavengerreceptor activity

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