Native Human Coagulation Factor XIII, A1 Polypeptide


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Native Human Coagulation Factor XIII, A1 Polypeptide

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Cat.No. : F13A1-5399H
Product Overview : Native Human F13A1 was expressed in Human plasma and molecular weight is 312 kDa.
Description : Human F13A1is producted from Factor XIII by cleavage with human alpha thrombin. FactorXIII is a tetramer composed of two pairs of chains held together by noncovalentbonds. Thrombin cleaves activation peptides from the alpha chains of FactorXIII (MW = 320 kDa) generating activated Factor XIIIa (MW = 312 kDa). The thrombinis subsequently removed via chromatography.
Source : Human plasma
Species : Human
Form : Frozenliquid containing 0.05 M Tris-HCl Buffer + 0.15 M NaCl + 0.001 M EDTA + 10 U/mlAprotinin + 20% Glycerol, pH 7.5.
Molecular Mass : 312 kDa
Endotoxin : < 0.1 ng/μg ofprotein.>
Purity : ≥95% by SDS-PAGEanalysis.
Storage : Store at -20°C.Stable for 12 months from delivery. Avoid repeated freeze-thaw cycles.
Concentration : 5.0 mg/ml
Gene Name : F13A1 coagulation factor XIII, A1 polypeptide [ Homo sapiens ]
Official Symbol : F13A1
Synonyms : F13A1; coagulation factor XIII, A1 polypeptide; F13A; coagulation factor XIII A chain; TGase; factor XIIIa; fibrinoligase; FSF, A subunit; coagulation factor XIIIa; transglutaminase A chain; transglutaminase. plasma; fibrin stabilizing factor, A subunit;
Gene ID : 2162
mRNA Refseq : NM_000129
Protein Refseq : NP_000120
MIM : 134570
UniProt ID : P00488
Chromosome Location : 6p24.2-p23
Pathway : Common Pathway, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem;
Function : metal ion binding; protein-glutamine gamma-glutamyltransferase activity; protein-glutamine gamma-glutamyltransferase activity; transferase activity, transferring acyl groups;

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