Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 2, GST-tagged
| Cat.No. : | MAP3K2-1258H |
| Product Overview : | Recombinanthuman full length MAP3K2, GST-tagged, is expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | MAP3K2-1258H | ||
| Description : | MAP3K2 isa serine/threonine kinase that activates kinases involved in the MAP kinasesignaling pathway. The protein encoded by this gene is a member ofserine/threonine protein kinase family. This kinase preferentially activatesother kinases involved in the MAP kinase signaling pathway. This kinase hasbeen shown to directly phosphorylate and activate Ikappa B kinases, and thusplays a role in NF-kappa B signaling pathway. This kinase has also been foundto bind and activate protein kinase C-related kinase 2, which suggests itsinvolvement in a regulated signaling process. | ||
| Source : | Insect cells | ||
| Species : | Human | ||
| Form : | Liquid in50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mMDTT + 50% glycerol. | ||
| Molecular Weight : | 97.2 kDa | ||
| Specific Activity : | 355 nmoleof phosphate transferred to myelin basic protein (MBP) per minute per mg of totalprotein at 30°C. Activity determined at a final protein concentration of 1.39μg/ml in acoupled assay. | ||
| Concentration : | 0.3 mg/ml | ||
| Storage : | Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles. | ||
| OfficialSymbol : | MAP3K2 | ||
| nullValue_other : |
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| Gene Name : | MAP3K2 mitogen-activatedprotein kinase kinase kinase 2 [ Homo sapiens ] |
| Synonyms : | MAP3K2; mitogen-activatedprotein kinase kinase kinase 2; MEKK2; MAPK/ERK kinase kinase 2;MEKK2B; OTTHUMP00000203817; OTTHUMP00000203818; OTTHUMP00000203819; EC2.7.11.25; MEK kinase 2; MAPKKK2; MAP/ERK kinasekinase 2 |
| Gene ID : | 10746 |
| mRNA Refseq : | NM_006609 |
| Protein Refseq : | NP_006600 |
| MIM : | 609487 |
| UniProt ID : | Q9Y2U5 |
| Chromosome Location : | 2q14.3 |
| Pathway : | EGFR1 SignalingPathway; ErbB1 downstream signaling; Gap junction; GnRH signaling pathway; InsulinSignaling; MAPK Cascade; MAPK signaling pathway; TNF-alpha/NF-kB SignalingPathway; Trk receptor signaling mediated by the MAPK pathway |
Products Types
| ◆ Recombinant Protein | ||
| MAP3K2-1358H | Recombinant Human MAP3K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| Map3k2-3929M | Recombinant Mouse Map3k2 Protein, Myc/DDK-tagged | +Inquiry |
| MAP3K2-351H | Recombinant Human MAP3K2, GST-tagged, Active | +Inquiry |
| MAP3K2-30191TH | Recombinant Human MAP3K2 | +Inquiry |
| ◆ Lysates | ||
| MAP3K2-4506HCL | Recombinant Human MAP3K2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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