Human MAP3K2 Knockdown Cell Lysate

• Cat.No.: MAP3K2-503HKCL
• Product Overview: WB-validated MAP3K2 Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 70 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg MAP3K2 KD HT-1080 cell lysate
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Gap junction, GnRH signaling pathway, MAPK signaling pathway
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: MAP3K2 mitogen-activated protein kinase kinase kinase 2 [ Homo sapiens (human) ]
• Official Symbol: MAP3K2
• Synonyms: MAP3K2; mitogen-activated protein kinase kinase kinase 2; MEKK2; MAP/ERK kinase kinase 2; MEKK2B; MEKK 2; MEK kinase 2; MAPK/ERK kinase kinase 2
• Gene ID: 10746
• mRNA Refseq: NM_006609
• Protein Refseq: NP_006600
• MIM: 609487
• UniProt ID: Q9Y2U5