Recombinant Human p21 Protein (Cdc42/Rac)-Activated Kinase 2, GST-tagged

• Cat.No.: PAK2-1282H
• Product Overview: Recombinant humanfull length PAK2, GST-tagged. Its molecular weight is 85500 Dalton.

Specification

• Cat. No.: PAK2-1282H
• Description: PAK2 proteins arecritical effectors that link Rho GTPases to cytoskeleton reorganization andnuclear signaling. PAK2 proteins, a family of serine/threonine p21-activatingkinases, serve as targets for the small GTP binding proteins Cdc42 and RACand have been implicated in a wide range of biological activities.
• Source: Insect cells
• Species: Human
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
• Molecular Weight: 85.5 kDa
• Storage: Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: PAK2

Gene Information

• Gene Name: PAK2 p21 protein (Cdc42/Rac)-activatedkinase 2 [ Homo sapiens ]
• Synonyms: PAK2; p21 protein(Cdc42/Rac)-activated kinase 2; PAK65; PAKgamma; p21-activated kinase 2;S6/H4 kinase; p21 (CDKN1A)-activated kinase 2; EC 2.7.11.1; PAK-2; Gamma-PAK;p58; C-t-PAK2
• Gene ID: 5062
• mRNA Refseq: NM_002577
• Protein Refseq: NP_002568
• MIM: 605022
• UniProt ID: Q13177
• Chromosome Location: 3q29
• Pathway: Activation of Rac;Adaptive Immune System; Apoptosis; Apoptotic execution phase; Axon guidance;C-MYC pathway; CD28 co-stimulation; CDC42 signaling events; Costimulation bythe CD28 family; ErbB signaling pathway; Focal adhesion; MAPK signalingpathway; Regulation of actin cytoskeleton; Renal cell carcinoma; T cellreceptor signaling pathway
• Function: ATP binding;identical protein binding; nucleotide binding; protein binding; proteinkinase activity; protein kinase binding; protein serine/threonine kinaseactivity; protein tyrosine kinase activator activity