Recombinant Human p21 Protein (Cdc42/Rac)-Activated Kinase 2, GST-tagged

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Recombinant Human p21 Protein (Cdc42/Rac)-Activated Kinase 2, GST-tagged

PAK2 Related Products

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Cat. No. : PAK2-1282H
Product Overview : Recombinant humanfull length PAK2, GST-tagged. Its molecular weight is 85500 Dalton.
Description : PAK2 proteins arecritical effectors that link Rho GTPases to cytoskeleton reorganization andnuclear signaling. PAK2 proteins, a family of serine/threonine p21-activatingkinases, serve as targets for the small GTP binding proteins Cdc42 and RACand have been implicated in a wide range of biological activities.
Source : Insect cells
Species : Human
Form : Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
Molecular Weight : 85.5 kDa
Storage : Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : PAK2
PDB rendering basedon 1e0a. :

Gene Name : PAK2 p21 protein (Cdc42/Rac)-activatedkinase 2 [ Homo sapiens ]
Synonyms : PAK2; p21 protein(Cdc42/Rac)-activated kinase 2; PAK65; PAKgamma; p21-activated kinase 2;S6/H4 kinase; p21 (CDKN1A)-activated kinase 2; EC 2.7.11.1; PAK-2; Gamma-PAK;p58; C-t-PAK2
Gene ID : 5062
mRNA Refseq : NM_002577
Protein Refseq : NP_002568
MIM : 605022
UniProt ID : Q13177
Chromosome Location : 3q29
Pathway : Activation of Rac;Adaptive Immune System; Apoptosis; Apoptotic execution phase; Axon guidance;C-MYC pathway; CD28 co-stimulation; CDC42 signaling events; Costimulation bythe CD28 family; ErbB signaling pathway; Focal adhesion; MAPK signalingpathway; Regulation of actin cytoskeleton; Renal cell carcinoma; T cellreceptor signaling pathway
Function : ATP binding;identical protein binding; nucleotide binding; protein binding; proteinkinase activity; protein kinase binding; protein serine/threonine kinaseactivity; protein tyrosine kinase activator activity

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