"Gdf6" Related Products

Recombinant Mouse Growth Differentiation Factor 6

Cat. No. : Gdf6-722M
Product Overview : Recombinant Mouse Gdf6protein was expressed in E. coli. Thr335-Arg454.
Description : Gdf6, also known asbone morphogenetic protein 13 (BMP13) or cartilage-derived morphogeneticprotein 2 (CDMP2), is a member of the bone morphogenetic protein (BMP) familywhich belongs to the transforming growth factor β (TGFβ) superfamily. Themature Gdf6 with 120 amino acids is a homodimeric protein containing thecharacteristic seven conserved cysteine residues. Gdf5, Gdf6 and Gdf7, whichshare 80-86% identity, define a new subgroup within the BMP family.
Source : E. coli-derived.
Form : Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
N-terminalSequence : Thr335
Molecular Weight : 13.7 kDa
Activity : Measuredby its ability to induce alkaline phosphatase production by ATDC5 mousechondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351. The ED50for this effect is typically 4-16 μg/mL.
Endotoxin Level : <1.0 EUper 1 μg of the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 300μg/mL in sterile 4 mM HCl that containing at least 0.1% human or bovine serumalbumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8 °C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution.
Gene Name : Gdf6 growth differentiationfactor 6 [ Mus musculus ]
Official Symbol : Gdf6
Synonyms : Gdf6; growthdifferentiation factor 6; BMP13; GDF16; growth/differentiation factor 6;GDF-6; growth differentiation factor 16; growth/differentiation factor 16
Gene ID : 242316
mRNA Refseq : NM_013526
Protein Refseq : NP_038554
UniProt ID : P43028
Chromosome Location : 4 A1; 4
Pathway : TGF-beta signalingpathway
Function : cytokine activity;growth factor activity; protein homodimerization activity

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