Active Recombinant Human ADAM Metallopeptidase Domain 8, His-tagged
Cat.No. : | ADAM8-525H |
Product Overview : | Recombinant Human ADAM8protein was expressed in Murine myeloma cell line with a C-terminal 6-His tag.Met1-Pro497. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ADAM8-525H |
Description : | ADAM8, also known ascell surface antigen MS2 or CD156a, is a member of the ADAM family that containsa disintegrin and metalloproteaselike domain. ADAM8 can cleave a variety of substratesand has been shown as a sheddase for the low affinity IgE receptor CD23 andthe neural recognition molecule CHL1. Expression and regulation studiessuggest that ADAM8 is a novel osteoclast stimulating factor and may play arole in asthma. |
Source : | Mammalian cells |
Form : | Supplied as a 0.2 μmfiltered solution in Glycerol, Tris, NaCl and CaCl2. |
N-terminalSequence : | Glu158 |
Molecular Weight : | 38 kDa |
Activity : | Measuredby its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-DpaRSSSR-NH2,The specific activity is > 1 pmol/min/μg, as measured under the described conditions. |
Endotoxin Level : | < 1.0 EU per 1 μgof the protein by the LAL method. |
SDS-PAGE : | 42 kDa, reducingconditions. |
Purity : | > 90%, by SDSPAGEunder reducing conditions and visualized by silver stain. |
Storage : | Use a manual defrostfreezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt,-20 to -70°C as supplied. 3 months, -20 to -70°C under sterile conditionsafter opening. |
Gene Name : | ADAM8 ADAM metallopeptidasedomain 8 [ Homo sapiens ] |
Official Symbol : | ADAM8 |
Synonyms : | ADAM8; ADAMmetallopeptidase domain 8; MS2; CD156; CD156a; disintegrin andmetalloproteinase domain-containing protein 8; cell surface antigen MS2;human leukocyte differentiation antigen; a disintegrin and metalloproteinasedomain 8; EC 3.4.24.- |
Gene ID : | 101 |
mRNA Refseq : | NM_001109 |
Protein Refseq : | NP_001100 |
MIM : | 602267 |
UniProt ID : | P78325 |
Chromosome Location : | 10q26.3 |
Function : | calcium ion binding;cell adhesion molecule binding; metalloendopeptidase activity;metallopeptidase activity; peptidase activity; protein binding; protein self-association;zinc ion binding |
Products Types
◆ Recombinant Protein | ||
ADAM8-320M | Recombinant Mouse ADAM8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAM8-2421H | Recombinant Human ADAM8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAM8-086H | Recombinant Human ADAM8 Protein, His-tagged | +Inquiry |
ADAM8-004H | Recombinant Human ADAM8 Protein, C-His-tagged | +Inquiry |
ADAM8-1094H | Recombinant Human ADAM8 Protein (Glu145-Asn494), N-His tagged | +Inquiry |
◆ Lysates | ||
ADAM8-855CCL | Recombinant Cynomolgus ADAM8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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