Recombinant Human ADAM8 Protein, His tagged

• Cat.No.: ADAM8-001H
• Product Overview: Recombinant Human ADAM8 Protein with His tag was expressed in Insect Cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 158-653 aa
• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
• AASequence: MEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSHHHHHHHH
• Molecular Mass: 55 kDa
• Endotoxin: < 1 EU/μg of protein (determined by LAL method)
• Purity: > 80% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile PBS, pH7.4, 0.05% SKL
• Concentration: 1 mg/mL by BCA

Gene Information

• Gene Name: ADAM8 ADAM metallopeptidase domain 8 [ Homo sapiens (human) ]
• Official Symbol: ADAM8
• Synonyms: ADAM8; ADAM metallopeptidase domain 8; a disintegrin and metalloproteinase domain 8; disintegrin and metalloproteinase domain-containing protein 8; CD156; MS2; cell surface antigen MS2; human leukocyte differentiation antigen; MGC134985
• Gene ID: 101
• mRNA Refseq: NM_001109
• Protein Refseq: NP_001100
• MIM: 602267
• UniProt ID: P78325