"Fzd7" Related Products


Recombinant Mouse Frizzled Homolog 7 (Drosophila), Fc-tagged

Cat. No. : Fzd7-589M
Product Overview : RecombinantMouse Fzd7 protein was expressed in Murine myeloma cell line with the Fc partof Human IgG1 Pro100-Lys330 (C-terminus) and Mouse Frizzled-7 Gln33-Leu185(N-terminus).
Description : Fzd7 is a member ofthe Frizzled family of unconventional G-protein-coupled glycoprotein receptorsfor the Wnt signaling pathway. The Wnt genes encode a large family ofglycoproteins that are essential in development and tissue maintenance.
Source : Murine myeloma cellline, NS0-derived
Form : Supplied as a 0.2 μmfiltered solution in PBS.
N-terminal Sequence : Gln33 predicted
Molecular Weight : 43 kDa
Activity : Measured by itsability to bind biotinylated Wnt-5a in a functional ELISA with an estimated KD< 5 nM.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
SDS-PAGE : 55-60 kDa, reducingconditions
Purity : >95%, by SDS-PAGEunder reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 200μg/mL in sterile PBS.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to-70 °C under sterile conditions after reconstitution.
Gene Name : Fzd7 frizzled homolog 7(Drosophila) [ Mus musculus ]
Official Symbol : Fzd7
Synonyms : Fzd7;frizzled homolog 7 (Drosophila); Fz7; OTTHUMP00000022716; frizzled-7;Fz-7; mFz7
Gene ID : 14369
mRNA Refseq : NM_008057
Protein Refseq : NP_032083
UniProt ID : Q6P551
Chromosome Location : 1
Pathway : Basal cellcarcinoma; Class B/2 (Secretin family receptors); GPCR ligand binding; HTLV-Iinfection; Melanogenesis; Pathways in cancer; Signal Transduction; Signalingby GPCR; Wnt Signaling Pathway; Wnt signaling network
Function : G-proteincoupled receptor activity; PDZ domain binding; Wnt-activated receptoractivity; Wnt-protein binding

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