"Fzd7" Related Products

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Recombinant Mouse Frizzled Homolog 7 (Drosophila), Fc-tagged

Cat. No.: Fzd7-589M
Product Overview: RecombinantMouse Fzd7 protein was expressed in Murine myeloma cell line with the Fc partof Human IgG1 Pro100-Lys330 (C-terminus) and Mouse Frizzled-7 Gln33-Leu185(N-terminus).
Description: Fzd7 is a member ofthe Frizzled family of unconventional G-protein-coupled glycoprotein receptorsfor the Wnt signaling pathway. The Wnt genes encode a large family ofglycoproteins that are essential in development and tissue maintenance.
Source: Murine myeloma cellline, NS0-derived
Form: Supplied as a 0.2 μmfiltered solution in PBS.
N-terminal Sequence: Gln33 predicted
Molecular Weight: 43 kDa
Activity: Measured by itsability to bind biotinylated Wnt-5a in a functional ELISA with an estimated KD< 5 nM.
Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
SDS-PAGE: 55-60 kDa, reducingconditions
Purity: >95%, by SDS-PAGEunder reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at 200μg/mL in sterile PBS.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to-70 °C under sterile conditions after reconstitution.
Gene Name: Fzd7 frizzled homolog 7(Drosophila) [ Mus musculus ]
Official Symbol: Fzd7
Synonyms: Fzd7;frizzled homolog 7 (Drosophila); Fz7; OTTHUMP00000022716; frizzled-7;Fz-7; mFz7
Gene ID: 14369
mRNA Refseq: NM_008057
Protein Refseq: NP_032083
UniProt ID: Q6P551
Chromosome Location: 1
Pathway: Basal cellcarcinoma; Class B/2 (Secretin family receptors); GPCR ligand binding; HTLV-Iinfection; Melanogenesis; Pathways in cancer; Signal Transduction; Signalingby GPCR; Wnt Signaling Pathway; Wnt signaling network
Function: G-proteincoupled receptor activity; PDZ domain binding; Wnt-activated receptoractivity; Wnt-protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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