"IL34" Related Products


Recombinant Human Interleukin 34, His-tagged

Cat. No.: IL34-652H
Product Overview: RecombinantHuman IL34 protein was expressed in Murine myeloma cell line. Asn21-Pro242,with a C-terminal 6-His tag.
Description: IL34 issecreted as a homodimer consisting of 39 kDa monomers. It belongs to no knowncytokine family. Human IL34 is synthesized as a242 amino acid (aa) precursor that contains a 20 aa signal sequence and a 222aa mature chain. The mature chain contains one potential site of N-linkedglycosylation. Human IL34 is 71% identicaltomouse IL34 on theamino acid level. IL34 is expressed in various tissues, includingthe heart, brain, liver, kidney, spleen, thymus, testes, ovary, smallintestine, prostate, and colon, and is most abundant in the spleen.
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 um filtered solution in PBS and NaCl with BSA as a carrier protein.
N-terminalSequence: Asn21
MolecularWeight: 26.1 kDa
Activity: Measuredin a cell proliferation assay using human peripheral blood monocytes. The ED 50for this effect is typically 0.75-3.75 ng/mL.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 35-38kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstituteat 100μg/mL in sterile PBS containing at least 0.1% human or bovine serumalbumin.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 6 monthsfrom date of receipt, -20 to -70°C as supplied. 3 months,-20to-70°C under sterile conditions after opening.
Gene Name: IL34 interleukin 34 [ Homosapiens ]
Official Symbol: IL34
Synonyms: IL34; interleukin 34; IL-34; C16orf77; interleukin-34; chromosome 16 open reading frame 77; MGC34647
Gene ID: 146433
mRNA Refseq: NM_001172771
Protein Refseq: NP_001166242
MIM: 612081
UniProt ID: Q6ZMJ4
Chromosome Location: 16q22.1
Function: cytokine activity;growth factor activity; macrophage colony-stimulating factor receptor binding

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