Recombinant Mouse Il34 Protein, His-tagged
| Cat.No. : | Il34-7418M |
| Product Overview : | Recombinant Mouse IL34 protein, fused to His-tag at N-terminus, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. |
| Source : | E. coli |
| Species : | Mouse |
| Tag : | His |
| Form : | Liquid |
| Molecular Mass : | 26.8 kDa |
| Protein length : | 21-235 |
| AA Sequence : | MGSSHHHHHHSSGLVPRGSHMNENL EIWTLTQDKECDLTGYLRGKLQYKN RLQYMKHYFPINYRIAVPYEGVLRV ANITRLQKAHVSERELRYLWVLVSL NATESVMDVLLEGHPSWKYLQEVQT LLENVQRSLMDVEIGPHVEAVLSLL STPGLSLKLVRPKALLDNCFRVMEL LYCSCCKQSPILKWQDCELPRLHPH SPGSLMQCTATNVYPLSRQTPTSLP GSPSSSHGSLP |
| Purity : | > 85 % by SDS-PAGE |
| Stability : | Shelf life: one year from despatch. |
| Storage : | Store undiluted at 2-8 centigrade for one week or (in aliquots) at -20 to -80 centigrade for longer. Avoid repeated freezing and thawing. |
| Concentration : | 0.5 mg/mL (determined by BRADFORD assay) |
| Storage Buffer : | 20 mM Tris-HCl buffer (pH 8.0) containing 10 % Glycerol. |
| Gene Name : | Il34 interleukin 34 [ Mus musculus (house mouse) ] |
| Official Symbol : | Il34 |
| Synonyms : | Il34; interleukin 34; AI593503; 2010004A03Rik; interleukin-34 |
| Gene ID : | 76527 |
| mRNA Refseq : | NM_001135100 |
| Protein Refseq : | NP_001128572 |
| UniProt ID : | Q8R1R4 |
Products Types
| ◆ Lysates | ||
| IL34-2783MCL | Recombinant Mouse IL34 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (6)
Ask a questionThere are no clear studies showing the effect of IL34 on tumor prognosis.
Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.
May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.
No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.
Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.
The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.
Customer Reviews (3)
Write a reviewIL34 has shown good biocompatibility and safety in related experiments. -
When using IL34 for experiments, the experimental conditions and results are highly repeatable. -
Quality is stable and reliable, with no significant differences between batches. -
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