Recombinant Mouse Il34 Protein, His-tagged

Cat.No. : Il34-7418M
Product Overview : Recombinant Mouse IL34 protein, fused to His-tag at N-terminus, was expressed in E. coli.
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  • Gene Information
  • Related Products
Description : Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Source : E. coli
Species : Mouse
Tag : His
Form : Liquid
Molecular Mass : 26.8 kDa
Protein length : 21-235
AA Sequence : MGSSHHHHHHSSGLVPRGSHMNENL EIWTLTQDKECDLTGYLRGKLQYKN RLQYMKHYFPINYRIAVPYEGVLRV ANITRLQKAHVSERELRYLWVLVSL NATESVMDVLLEGHPSWKYLQEVQT LLENVQRSLMDVEIGPHVEAVLSLL STPGLSLKLVRPKALLDNCFRVMEL LYCSCCKQSPILKWQDCELPRLHPH SPGSLMQCTATNVYPLSRQTPTSLP GSPSSSHGSLP
Purity : > 85 % by SDS-PAGE
Stability : Shelf life: one year from despatch.
Storage : Store undiluted at 2-8 centigrade for one week or (in aliquots) at -20 to -80 centigrade for longer. Avoid repeated freezing and thawing.
Concentration : 0.5 mg/mL (determined by BRADFORD assay)
Storage Buffer : 20 mM Tris-HCl buffer (pH 8.0) containing 10 % Glycerol.
Gene Name : Il34 interleukin 34 [ Mus musculus (house mouse) ]
Official Symbol : Il34
Synonyms : Il34; interleukin 34; AI593503; 2010004A03Rik; interleukin-34
Gene ID : 76527
mRNA Refseq : NM_001135100
Protein Refseq : NP_001128572
UniProt ID : Q8R1R4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the effect of IL34 on tumor prognosis? 09/19/2022

There are no clear studies showing the effect of IL34 on tumor prognosis.

What are the advantages of IL34 over other treatments? 05/14/2022

Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.

What is the mechanism of action of IL34 in the treatment of tumor? 07/09/2020

May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.

How is the clinical trial of IL34 progressing? 04/02/2020

No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.

How does IL34 affect the immune system? 03/26/2020

Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.

How to evaluate the efficacy of IL34? 01/31/2019

The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.

Customer Reviews (3)

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Reviews
05/10/2021

    IL34 has shown good biocompatibility and safety in related experiments. -

    01/19/2020

      When using IL34 for experiments, the experimental conditions and results are highly repeatable. -

      10/24/2019

        Quality is stable and reliable, with no significant differences between batches. -

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