Recombinant Mouse Il34 Protein, His-tagged

• Cat.No.: Il34-7418M
• Product Overview: Recombinant Mouse IL34 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Specification

• Description: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Liquid
• Molecular Mass: 26.8 kDa
• Protein length: 21-235
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMNENL EIWTLTQDKECDLTGYLRGKLQYKN RLQYMKHYFPINYRIAVPYEGVLRV ANITRLQKAHVSERELRYLWVLVSL NATESVMDVLLEGHPSWKYLQEVQT LLENVQRSLMDVEIGPHVEAVLSLL STPGLSLKLVRPKALLDNCFRVMEL LYCSCCKQSPILKWQDCELPRLHPH SPGSLMQCTATNVYPLSRQTPTSLP GSPSSSHGSLP
• Purity: > 85 % by SDS-PAGE
• Stability: Shelf life: one year from despatch.
• Storage: Store undiluted at 2-8 centigrade for one week or (in aliquots) at -20 to -80 centigrade for longer. Avoid repeated freezing and thawing.
• Concentration: 0.5 mg/mL (determined by BRADFORD assay)
• Storage Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10 % Glycerol.

Gene Information

• Gene Name: Il34 interleukin 34 [ Mus musculus (house mouse) ]
• Official Symbol: Il34
• Synonyms: Il34; interleukin 34; AI593503; 2010004A03Rik; interleukin-34
• Gene ID: 76527
• mRNA Refseq: NM_001135100
• Protein Refseq: NP_001128572
• UniProt ID: Q8R1R4