Recombinant Human Anti-Mullerian Hormone Receptor, Type II, Fc-tagged


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Recombinant Human Anti-Mullerian Hormone Receptor, Type II, Fc-tagged

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Cat. No. : AMHR2-5601H
Product Overview : Recombinant Human AMHR2protein was expressed in Murine myeloma cell line with the Fc part of humanIgG1 Pro100-Lys330 (C-terminus) and Pro18-Ser144 (N-terminus).
Description : Human AMHR2 is an 82kDa serine/threonine receptor with a single transmembrane domain that belongsto the family of type II receptors of the TGF β superfamily. The AMHR2precursor is 573 amino acids (aa) in length, with a 17 aa signal sequence, a127 aa extracellular region that also contains two potential Nlinkedglycosylation sites, a 26 aa transmembrane region, and a 403 aa cytoplasmicregion that contains the serine/threonine kinase domain.
Source : Murine myeloma cellline, NS0-derived
Form : Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence : Pro18
Molecular Weight : 40.2 kDa
Activity : Measuredby its ability to bind rhAMHR2 in afunctional ELISA.
Endotoxin Level : <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE : 60-65kDa, reducing conditions
Purity : >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstituteat 100 μg/mL in PBS
Storage : Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt,-20 to -70°C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : AMHR2 anti-Mullerian hormonereceptor, type II [ Homo sapiens ]
Official Symbol : AMHR2
Synonyms : AMHR2; anti-Mullerianhormone receptor, type II; AMHR; MRII; MISR2; MISRII; anti-Muellerian hormonetype-2 receptor; AMH type II receptor; MIS type II receptor; anti-Muellerianhormone type II receptor; Mullerian inhibiting substance type II receptor; EC2.7.11.30; OTTHUMP00000242707; OTTHUMP00000242708; OTTHUMP00000242709
Gene ID : 269
mRNA Refseq : NM_001164690
Protein Refseq : NP_001158162
MIM : 600956
UniProt ID : Q16671
Chromosome Location : 12q13
Pathway : ALK2 signalingevents; Cytokine-cytokine receptor interaction; TGF-beta signaling pathway
Function : ATP binding; hormonebinding; metal ion binding; nucleotide binding; receptor activity; transforminggrowth factor beta receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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