"Ccl2" Related Products


Recombinant Rat Chemokine (C-C motif) Ligand 2

Cat. No.: Ccl2-469R
Product Overview: Recombinant Rat Ccl2protein was expressed in Murine myeloma cell line. Gln24-Asn148.
Description: Rat Ccl2 is a memberof the β (CC) subfamily of chemokines that is a chemoattractant for monocytesand basophils but not eosinophils or neutrophils. Rat Ccl2 is secreted as a 14kDa glycoprotein monomer but noncovalent dimers probably occur. The first fiveamino acids of the mature protein are essential for activity; deletion of theN-terminal glutamine, which is pyrrolidone carboxylic acidmodified, dramaticallydecreases activity on basophils and, surprisingly, stimulates eosinophil chemotaxis.
Source: Murine myeloma cell line,NS0-derived
Form: Lyophilized from a 0.2μm filtered solution in PBS with Trehalose and with BSA as a carrier protein.
N-terminalSequence: No results obtained:Gln24 predicted
Molecular Weight: 14 kDa
Activity: Measuredby its ability to chemoattract human CCR2A transfected BaF3 mouse proB cells.The ED50 for this effect is typically 30-150 ng/mL.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
Purity: >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstituteat 10 μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage: Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months,-20 to -70°C under sterile conditions after reconstitution.
Gene Name: Ccl2 chemokine(C-C motif) ligand 2 [ Rattus norvegicus ]
Official Symbol: Ccl2
Synonyms: Ccl2; chemokine(C-C motif) ligand 2; MCP-1; Scya2; Sigje; C-C motif chemokine 2; small induciblegene JE; small inducible cytokine A2; small-inducible cytokine A2; monocyte chemotacticprotein 1; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1;immediate-early serum-responsive JE protein; immediate-early serum-responsiveprotein JE; Je; Mcp1
Gene ID: 24770
mRNA Refseq: NM_031530
Protein Refseq: NP_113718
UniProt ID: P14844
Chromosome Location: 10q26
Pathway: Chemokine signaling pat
Function: CCR2 chemokine receptorbinding; G-protein coupled receptor binding; chemokine activity; heparin binding

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.