"AKAP7" Related Products

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Recombinant Human A-kinase (PRKA) Anchor Protein 7, His-tagged

Cat. No.: AKAP7-2395H
Product Overview: Recombinant humanAKAP7 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques.
Description: AKAP7 (A-kinaseanchor protein 7 isoform gamma isoform alpha) , also known as AKAP18, belongsto the A-kinase anchoring protein (AKAP) family, a group of functionallyrelated proteins that bind to a regulatory subunit (RII) of cAMP-dependentprotein kinase A (PKA) and target the enzyme to specific subcellularcompartments. AKAP 7 is expressed in brain, heart, lung, pancreas andskeletal muscle. AKAP 7 binds PKA to the plasma membrane, and permitsfunctional coupling to the L-type calcium channel
Form: Liquid. In 20 mMTris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl
Molecular Weight: 11.5kDa (105aa),confirmed by MALDI-TOF
Purity: > 90% by SDS -PAGE
Concentration: 1mg/ml (determinedby Bradford assay)
Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMGQLCC FPFSRDEGKI SEKNGGEPDD AELVRLSKRL VENAVLKAVQ QYLEETQNKNKPGEGSSVKT EAADQNGNDN ENNRK
Storage: Stored at +4°C shortterm (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Officialsymbol: AKAP7
Gene Name: AKAP7 A kinase (PRKA) anchorprotein 7 [Homo sapiens]
Synonyms: A kinase(PRKA) anchor protein 7; A-kinase anchor protein 7; A-kinase anchor protein 7isoform alpha; A-kinase anchor protein 7 isoform gamma; Protein kinaseA-anchoring protein 7 isoform gamma; A-kinase anchor protein 7 isoforms alphaand beta; Protein kinase A-anchoring protein 7 isoforms alpha/beta; A-kinaseanchor protein 9 kDa; A-kinase anchor protein 18 kDa; A-kinase anchorprotein, 18-kD; A-kinase anchoring protein 18; protein kinase A anchoringprotein 7; AKAP15; AKAP18; AKAP 18; OTTHUMP00000017200; OTTHUMP00000017201;OTTHUMP00000017202; OTTHUMP00000239966; AKAP-7 isoform gamma; AKAP-7 isoformsalpha and beta
Gene ID: 9465
mRNA Refseq: NM_004842
Protein Refseq: NP_004833
MIM: 604693
UniProt ID: Q6P4D3
Chromosome Location: 6q23
Pathway: GProtein Signaling Pathways
Function: AMPbinding; catalytic activity; kinase activity; protein C-terminus binding;protein complex scaffold; protein domain specific binding; protein kinase Abinding; protein kinase A binding; protein kinase A regulatory subunitbinding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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