Recombinant Human Transforming Growth Factor, Beta 2, Dimeric Form

• Cat.No.: TGFB2-004N
• Product Overview: It is produced by transient expression of TGFβ-2 in non-transgenic plant. Recombinant human TGFβ-2 is purified by sequential chromatography (FPLC). This product contains no animal–derived components or impurities.

Specification

• Cat. No.: TGFB2-004N
• Description: Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a potent cytokine that modulates embryonic development, bone formation, mammary development, wound healing, hematopoiesis, cell cycle progression and the production of the extracellular matrix.
• Source: Nicotiana benthamiana.
• Formulation: Lyophilized from a buffer of Tris HCl 0.05M pH 7.4.
• Molecular formula: C602H909N167O171S10
• Extinction coefficient: E0.1% = 2.02 (A280 nm).
• Molecular weight: 25.0 kDa
• p.l: 7.72
• Purity assay: >95% as determinate by SDS-PAGE gel.
• Endotoxin level: < 0.04 EU/ μg protein (LAL method)
• Biological Activity: The biological activity of TGF-β2 is measured in culture by its ability to inhibit the mink lung epithelial cells proliferation. (ED50 is defined as the effective concentration of growth factor that elicits a 50% inhibition in cell growth in a cell based bioassay)
• Storage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage. Repeated freezing and thawing is not recommended.

Gene Information

• Gene Name: TGFB2 transforming growth factor, beta 2 [ Homo sapiens ]
• Official Symbol: TGFB2
• Synonyms: TGFB2; transforming growth factor, beta 2; MGC116892; TGF-beta2; transforming growth factor, beta 2
• Gene ID: 7042
• mRNA Refseq: NM_001135599
• Protein Refseq: NP_001129071
• MIM: 190220
• UniProt ID: P61812
• Chromosome Location: 1q41
• Function: beta-amyloid binding; cytokine activity; protein heterodimerization activity; growth factor activity; type II transforming growth factor beta receptor binding; receptor signaling protein serine/threonine kinase activity