Recombinant Human FASTK, GST-tagged
| Cat.No. : | FASTK-801H |
| Product Overview : | Recombinant full-length human FASTK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | FASTK-801H |
| Description : | FASTK or Fas-Activated Serine/Threonine Kinase is a member of the serine/ thre- onine protein kinase family that becomes rapidly activated during Fas-mediatedapoptosis in Jurkat cells and in response to Fas receptor ligation. FASTK interacts with and phosphorylates TIA1 which is an apoptosis-promoting nuclear RNA- binding protein. FAST K influences alternative pre-mRNA splicing by affecting the activity of TIA-1/TIAR. FASTK is a strong inducer of lymphocyte apoptosis. FASTK is the component of the molecular cascade that involved in FAS-mediated apoptosis. FASTK is highly expreesed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. |
| Source : | Sf9 cells |
| Species : | Human |
| Predicted MolecularMass : | ~84 kDa |
| Formulation : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| SpecificActivity : | 1.0 nmol/min/mg |
| Applications : | WB |
| Purity : | >70% |
| Concentration : | 0.05 μg/μl |
| Stability& Storage : | Store product at –70°C. For optimal storage, aliquottarget into smaller quantities after centrifugation and store at recommended temperature. For most favorableperformance, avoid repeated handling and multiple freeze/thaw cycles. |
| OfficialSymbol : | FASTK |
| Gene Name : | FASTK Fas-activated serine/threonine kinase [ Homo sapiens ] |
| Synonyms : | FASTK; Fas-activated serine/threonine kinase; FAST; fas-activated serine/threonine kinase; FAST kinase; EC 2.7.11.8; Fas activated serine threonine kinase; FASTK_HUMAN; FLJ13079 |
| Gene ID : | 10922 |
| mRNA Refseq : | NM_006712 |
| Protein Refseq : | NM_006712 |
| MIM : | 606965 |
| UniProt ID : | Q14296 |
| Chromosome Location : | 7q35 |
| Function : | ATP binding; Fas-activated serine/threonine kinase activity; protein binding; protein serine/threonine kinase activity |
Products Types
| ◆ Recombinant Protein | ||
| FASTK-02H | Recombinant Human FASTK Protein, Myc/DDK-tagged | +Inquiry |
| FASTK-01H | Recombinant Human FASTK Protein, His-tagged | +Inquiry |
| Fastk-722R | Recombinant Rat Fastk Protein, His-tagged | +Inquiry |
| FASTK-721H | Recombinant Human FASTK Protein, His-tagged | +Inquiry |
| Fastk-2957M | Recombinant Mouse Fastk Protein, Myc/DDK-tagged | +Inquiry |
| ◆ Lysates | ||
| FASTK-6323HCL | Recombinant Human FASTK 293 Cell Lysate | +Inquiry |
| FASTK-6322HCL | Recombinant Human FASTK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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