Recombinant Human Interferon, Gamma-Inducible Protein 30, His-tagged
Cat.No. : | IFI30-7185H |
Product Overview : | Recombinant human IFI30 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW: 22.5 kDa. |
- Specification
- Gene Information
- Related Products
Description : | IFI30, also as known as gamma-interferon-inducible lysosomal thiol reductase, belongs to the GILT family. This protein is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. This protein facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT. |
Molecular Mass : | 22.5 kDa (199aa) confirmed by MALDI-TOF |
Protein length : | 58-232aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMNAPLVN VTLYYEALCG GCRAFLIREL FPTWLLVMEI LNVTLVPYGN AQEQNVSGRW EFKCQHGEEE CKFNKVEACV LDELDMELAF LTIVCMEEFE DMERSLPLCL QLYAPGLSPD TIMECAMGDR GMQLMHANAQ RTDALQPPHE YVPWVTVNGK PLEDQTQLLT LVCQLYQGK |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | IFI30 interferon, gamma-inducible protein 30 [ Homo sapiens ] |
Official Symbol : | IFI30 |
Synonyms : | IFI30; interferon, gamma-inducible protein 30; GILT; IP30; IFI-30; gamma-interferon-inducible lysosomal thiol reductase; legumaturain; gamma-interferon-inducible protein IP-30; interferon gamma-inducible protein 30 preproprotein; MGC32056; EC 1.8; Legumaturain |
Gene ID : | 10437 |
mRNA Refseq : | NM_006332 |
Protein Refseq : | NP_006323 |
MIM : | 604664 |
UniProt ID : | P13284 |
Chromosome Location : | 19p13.1 |
Pathway : | Adaptive Immune System; Antigen processing and presentation; Cytokine Signaling in Immune system; Immune System; Interferon Signali |
Function : | oxidoreductase activity, acting on a sulfur group of donors |
Products Types
◆ Recombinant Protein | ||
IFI30-2648R | Recombinant Rat IFI30 Protein, His (Fc)-Avi-tagged | +Inquiry |
IFI30-4429M | Recombinant Mouse IFI30 Protein, His (Fc)-Avi-tagged | +Inquiry |
IFI30-991H | Recombinant Human IFI30 Protein, MYC/DDK-tagged | +Inquiry |
Ifi30-3476M | Recombinant Mouse Ifi30 Protein, Myc/DDK-tagged | +Inquiry |
IFI30-468H | Recombinant Human IFI30 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IFI30-1503HCL | Recombinant Human IFI30 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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