Recombinant Human Ring Finger Protein 4, His-tagged
Cat.No. : | RNF4-7193H |
Product Overview : | Recombinant human RNF4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 23.7 kDa. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin ligase RNF4, also known as RNF4, contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 30% glycerol, 1mM DTT. |
Molecular Mass : | 23.7 kDa (213aa) confirmed by MALDI-TOF. |
Protein length : | 1-190aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSTRKRR GGAINSRQAQ KRTREATSTP EISLEAEPIE LVETAGDEIV DLTCESLEPV VVDLTHNDSV VIVDERRRPR RNARRLPQDH ADSCVVSSDD EELSRDRDVY VTTHTPRNAR DEGATGLRPS GTVSCPICMD GYSEIVQNGR LIVSTECGHV FCSQCLRDSL KNANTCPTCR KKINHKRYHP IYI |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | RNF4 ring finger protein 4 [ Homo sapiens ] |
Official Symbol : | RNF4 |
Synonyms : | RNF4; ring finger protein 4; SLX5; SNURF; RES4-26; E3 ubiquitin-protein ligase RNF4; E3 ubiquitin ligase RNF4; small nuclear RING finger protein; EC=6.3.2; Protein SNURF |
Gene ID : | 6047 |
mRNA Refseq : | NM_002938 |
Protein Refseq : | NP_002929 |
MIM : | 602850 |
UniProt ID : | P78317 |
Chromosome Location : | 4p16.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem |
Function : | DNA binding; SUMO polymer binding; androgen receptor binding; nucleosome binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription factor binding; ubiquitin-protein ligase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
RNF4-314H | Recombinant Human RNF4 Protein, GST-tagged | +Inquiry |
RNF4-7685M | Recombinant Mouse RNF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
RNF4-4742R | Recombinant Rat RNF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
RNF4-0444H | Recombinant Human RNF4 Protein (G120-I190), Tag Free | +Inquiry |
RNF4-0445H | Recombinant Human RNF4 Protein (G120-I190), GST tagged | +Inquiry |
◆ Lysates | ||
RNF4-2276HCL | Recombinant Human RNF4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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