"CDC25C" Related Products

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Recombinant Human CDC25C (Active), GST-tagged

Cat.No.: CDC25C-1513H
Product Overview: Full-length recombinant human CDC25C was expressed in Sf9 insect cells using an N-terminal GST tag.
Description: CDC25C (also known as cell division cycle 25 homolog C) is a member of the CDC25 phosphatase family. CDC25C is highly conserved during evolution and it plays a key role in the regulation of cell division. CDC25C activates the partially purified p34 (cdc2)/cyclin B complex and directs the dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. CDC25C also suppresses p53-induced growth arrest. The regulation of CDC25B phosphorylation by p38 is a critical event for initiating the G2/M checkpoint after ultraviolet radiation.
Source: Sf9 Cells
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: 22 nmol/min/mg
Molecular Mass: ~84 kDa
Protein length: Full length
Purity: >70%
Applications: Phosphatase Assay, Western Blot
Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: CDC25C cell division cycle 25 homolog C (S. pombe) [ Homo sapiens ]
Official Symbol: CDC25C
Synonyms: CDC25C; cell division cycle 25 homolog C (S. pombe); CDC25, cell division cycle 25 homolog C (S. cerevisiae) , cell division cycle 25C; M-phase inducer phosphatase 3; PPP1R60; protein phosphatase 1; regulatory subunit 60; mitosis inducer CDC25; cell division cycle 25C; phosphotyrosine phosphatase; dual specificity phosphatase CDC25C; protein phosphatase 1, regulatory subunit 60; CDC25;
Gene ID: 995
mRNA Refseq: NM_001790
Protein Refseq: NP_001781
MIM: 157680
UniProt ID: P30307
Chromosome Location: 5q31
Pathway: Activation of ATR in response to replication stress, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem;
Function: WW domain binding; hydrolase activity; protein binding; protein kinase binding; protein tyrosine phosphatase activity;

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