Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human CDC25C, GST-tagged

Cat.No. : CDC25C-1513H
Product Overview : Full-length recombinant human CDC25C was expressed in Sf9 insect cells using an N-terminal GST tag.
  • Specification
  • Gene Information
  • Related Products
Description : CDC25C (also known as cell division cycle 25 homolog C) is a member of the CDC25 phosphatase family. CDC25C is highly conserved during evolution and it plays a key role in the regulation of cell division. CDC25C activates the partially purified p34 (cdc2)/cyclin B complex and directs the dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. CDC25C also suppresses p53-induced growth arrest. The regulation of CDC25B phosphorylation by p38 is a critical event for initiating the G2/M checkpoint after ultraviolet radiation.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 22 nmol/min/mg
Molecular Mass : ~84 kDa
Protein length : Full length
Purity : >70%
Applications : Phosphatase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : CDC25C cell division cycle 25 homolog C (S. pombe) [ Homo sapiens ]
Official Symbol : CDC25C
Synonyms : CDC25C; cell division cycle 25 homolog C (S. pombe); CDC25, cell division cycle 25 homolog C (S. cerevisiae) , cell division cycle 25C; M-phase inducer phosphatase 3; PPP1R60; protein phosphatase 1; regulatory subunit 60; mitosis inducer CDC25; cell division cycle 25C; phosphotyrosine phosphatase; dual specificity phosphatase CDC25C; protein phosphatase 1, regulatory subunit 60; CDC25;
Gene ID : 995
mRNA Refseq : NM_001790
Protein Refseq : NP_001781
MIM : 157680
UniProt ID : P30307
Chromosome Location : 5q31
Pathway : Activation of ATR in response to replication stress, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem;
Function : WW domain binding; hydrolase activity; protein binding; protein kinase binding; protein tyrosine phosphatase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (3)

Write a review
Reviews
03/02/2023

    Fast and timely shipment helped me to get satisfactory experimental results in short time.

    08/16/2022

      The staff was very nice, communicated with me positively and solved a lot of technical problems.

      03/12/2022

        The technician gave me a thorough introduction to the CDC25C protein so that I could understand its biochemical properties.

        Ask a Question for All CDC25C Products

        Required fields are marked with *

        My Review for All CDC25C Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends