Recombinant Human IRAK3, GST-tagged
Cat.No. : | IRAK3-7003H |
Product Overview : | Recombinant full-length human IRAK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | IRAK3 or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which is essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAKM mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~96 kDa |
Protein length : | Full length |
Purity : | >80% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | IRAK3 interleukin-1 receptor-associated kinase 3 [ Homo sapiens ] |
Official Symbol : | IRAK3 |
Synonyms : | IRAK3; interleukin-1 receptor-associated kinase 3; IRAK M; IL-1 receptor-associated kinase M; ASRT5; IRAKM; FLJ13601; |
Gene ID : | 11213 |
mRNA Refseq : | NM_001142523 |
Protein Refseq : | NP_001135995 |
MIM : | 604459 |
UniProt ID : | Q9Y616 |
Chromosome Location : | 12q13.13 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; |
Function : | ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
Irak3-3569M | Recombinant Mouse Irak3 Protein, Myc/DDK-tagged | +Inquiry |
IRAK3-1192H | Recombinant Human IRAK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRAK3-5051H | Recombinant Human IRAK3 Protein, GST-tagged | +Inquiry |
IRAK3-7076H | Recombinant Human IRAK3 protein, His-tagged | +Inquiry |
Irak3-2234M | Recombinant Mouse Irak3 protein, His&Myc-tagged | +Inquiry |
◆ Lysates | ||
IRAK3-5170HCL | Recombinant Human IRAK3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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