Recombinant Human ESM1, His-tagged

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Recombinant Human ESM1, His-tagged

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Cat.No. : ESM1-7082H
Product Overview : Recombinant human ESM1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description : Endothelial cell-specific molecule 1, also known as ESM1, is a proteoglycan secreted by endothelial cells and its mRNA expression is regulated by inflammatory cytokines. ESM1 expression has also been detected in different epithelia and in adipocytes. The expression of endocan is upregulated by TNF alpha, IL1 beta, or lipopolysaccharide and downregulated by IFN gamma. Genetically engineered cells overexpressing endocan has been shown to induce tumor formation, suggesting that ESM1 may be involved in the pathophysiology of tumor growth in vivo.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea,10% glycerol
Molecular Mass : 20.5 kDa (188aa)
Protein length : 20-184aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSWSNNYAV DCPQHCDSSE CKSSPRCKRT VLDDCGCCRV CAAGRGETCY RTVSGMDGMK CGPGLRCQPSNGEDPFGEEF GICKDCPYGT FGMDCRETCN CQSGICDRGT GKCLKFPFFQ YSVTKSSNRF VSLTEHDMAS GDGNIVREEV VKENAAGSPV MRKWLNPR
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml
Gene Name : ESM1 endothelial cell-specific molecule 1 [ Homo sapiens ]
Official Symbol : ESM1
Synonyms : ESM1; endothelial cell-specific molecule 1; ESM-1; endocan;
Gene ID : 11082
mRNA Refseq : NM_001135604
Protein Refseq : NP_001129076
MIM : 601521
UniProt ID : Q9NQ30
Chromosome Location : 5q11
Function : growth factor activity; insulin-like growth factor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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