"POFUT1" Related Products

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Recombinant Human POFUT1, His-tagged

Cat.No.: POFUT1-7213H
product overview: Recombinant human POFUT1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
description: GDP-fucose protein O-fucosyltransferase 1, also known as POUFUT1, is a member of the glycosyltransferase O-Fuc family. Highly expressed in pancreas, kidney, lung, heart, brain, liver, placenta and skeletal muscle, POFUT1 uses manganese to catalyze the attachment of fucose to a conserved serine or threonine residue on a protein accept. POFUT1 plays an important role in Notch signaling, as Notch ligands can serve as POFUT1 substrates.
source: E. coli
species: Human
tag: His
form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 10% glycerol
molecular mass: 43.7kDa (385aa)
protein length: 27-388aa
aa sequence: MGSSHHHHHH SSGLVPRGSH MGSGSWDPAG YLLYCPCMGR FGNQADHFLG SLAFAKLLNR TLAVPPWIEY QHHKPPFTNL HVSYQKYFKL EPLQAYHRVI SLEDFMEKLA PTHWPPEKRV AYCFEVAAQR SPDKKTCPMK EGNPFGPFWD QFHVSFNKSE LFTGISFSAS YREQWSQRFS PKEHPVLALP GAPAQFPVLE EHRPLQKYMV WSDEMVKTGE AQIHAHLVRP YVGIHLRIGS DWKNACAMLK DGTAGSHFMA SPQCVGYSRS TAAPLTMTMC LPDLKEIQRA VKLWVRSLDA QSVYVATDSE SYVPELQQLF KGKVKVVSLK PEVAQVDLYI LGQADHFIGN CVSSFTAFVK RERDLQGRPS SFFGMDRPPK LRDE
purity: >85% by SDS - PAGE
applications: SDS-PAGE
storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
concentration: 1 mg/ml
gene name: POFUT1 protein O-fucosyltransferase 1 [ Homo sapiens ]
official symbol: POFUT1
synonyms: POFUT1; protein O-fucosyltransferase 1; GDP-fucose protein O-fucosyltransferase 1; FUT12; KIAA0180; O Fuc T; O FUT; o-fucosyltransferase protein; peptide-O-fucosyltransferase 1; O-FUT; O-Fuc-T; O-FucT-1; MGC2482;
Gene ID: 23509
mrna refseq: NM_015352
protein refseq: NP_056167
mim: 607491
uniprot id: Q9H488
chromosome location: 20q11
pathway: Delta-Notch Signaling Pathway, organism-specific biosystem; Other types of O-glycan biosynthesis, organism-specific biosystem; Other types of O-glycan biosynthesis, conserved biosystem; Pre-NOTCH Expression and Processing, organism-specific biosystem; Pre-NOTCH Processing in the Endoplasmic Reticulum, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem;
function: fucosyltransferase activity; peptide-O-fucosyltransferase activity; transferase activity, transferring glycosyl groups;

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