| Cat. No. : |
CFHR5-922H |
| Description : |
A mutation in CHFR5 was found in patients with the disease CFHR5 nephropathy, which is a common cause of renal disease in Cyprus. The mutated form of the protein found in patients with this disease has impaired ability to bind to complement C3, suggesting that CFHR5 is important in protecting the kidneys from attack by the complement system. |
| Source : |
wheat germ |
| MolecularMass : |
90.8 kDa |
| Sequence : |
MLLLFSVILISWVSTVGGEGTLCDF PKIHHGFLYDEEDYNPFSQVPTGEV FYYSCEYNFVSPSKSFWTRITCTEE GWSP TPKCLRMCSFPFVKNGHSESSGLIH LEGDTVQIICNTGYSLQNNEKNISC VERGWSTPPICSFTKGECHVPILEA NVD AQPKKESYKVGDVLKFSCRKNLIRV GSDSVQCYQFGWSPNFPTCKGQVRS CGPPPQLSNGEVKEIRKEEYGHNEV V EYDCNPNFIINGPKKIQCVDGEWTT LPTCVEQVKTCGYIPELEYGYVQPS VPPYQHGVSVEVNCRNEYAMIGNNM ITCIN GIWTELPMCVATHQLKRCKIAGVNI KTLLKLSGKEFNHNSRIRYRCSDIF RYRHSVCINGKWNPEVDCTEKREQF CPPP PQIPNAQNMTTTVNYQDGEKVAVLC KENYLLPEAKEIVCKDGRWQSLPRC VESTAYCGPPPSINNGDTTSFPLSV YPPG STVTYRCQSFYKLQGSVTVTCRNKQ WSEPPRCLDPCVVSEENMNKNNIQL KWRNDGKLYAKTGDAVEFQCKFPHK A MISSPPFRAICQEGKFEYPICE |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer. |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Note : |
Best use within three months from the date of receipt of this protein. |
| OfficialSymbol : |
CFHR5 |
