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Active Recombinant Human CD40LG protein, hFc&Avi-tagged, Biotinylated

Cat.No. : CD40LG-280H
Product Overview : Biotinylated Recombinant Human CD40LG protein(NP_000065.1)(Met113-Leu261), fused with hFc tag and Avi tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : hFc&Avi
Form : Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 8.5.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Bio-activity : Immobilized Human CD40 His at 2 μg/mL (100 μL/well) can bind Human CD40 Ligand (ECD, hFc & AVI Tag), Biotinylated, the EC50 is 5-40 ng/mL.
Molecular Mass : The recombinant human CD40LG consists of 402 amino acids and predicts a molecular mass of 44.7 kDa.
Proteinlength : Met113-Leu261
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 85 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD40LG CD40 ligand [ Homo sapiens ]
Official Symbol : CD40LG
Synonyms : CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tumor necrosis factor (ligand) superfamily member 5; CD40-L; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; IGM; IMD3; HIGM1; T-BAM; TNFSF5;
Gene ID : 959
mRNA Refseq : NM_000074
Protein Refseq : NP_000065
MIM : 300386
UniProt ID : P29965

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Are there any ongoing clinical trials targeting CD40LG for autoimmune diseases? 11/01/2022

Yes, there are clinical trials investigating the modulation of CD40LG in autoimmune diseases, exploring its potential role in regulating immune responses that contribute to autoimmunity.

Can CD40LG be a potential target for the treatment of infectious diseases? 02/27/2021

Yes, research suggests that CD40LG modulation might be a viable strategy in the development of treatments for infectious diseases by enhancing immune responses.

How does the interaction between CD40LG and its receptor CD40 influence antibody production? 11/20/2020

The interaction between CD40LG and CD40 is crucial for the activation of B cells, leading to the production of antibodies and the development of an effective immune response.

How is CD40LG involved in the regulation of inflammatory responses? 08/26/2020

CD40LG is involved in modulating inflammatory responses by influencing the activation and function of immune cells, contributing to the regulation of the immune system.

In what ways is CD40LG being explored for its potential in vaccine development? 04/20/2020

CD40LG is being investigated as an adjuvant in vaccine development, aiming to enhance the immune response and improve the efficacy of vaccines against various diseases.

Customer Reviews (3)

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10/17/2022

    The reliable performance of the CD40LG protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.

    01/01/2022

      Its reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various fields of study.

      11/16/2020

        Their knowledgeable and responsive team assists in troubleshooting and finding solutions to any experimental challenges that may arise.

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