"ITGAM" Related Products

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Recombinant Human Integrin, Alpha M (Complement Component 3 Receptor 3 Subunit)

Cat. No.: ITGAM-4257H
Product Overview: CD11b Human Recombinant (aa 936-1154) expressed in E.coli, shows a 52 kDa band on SDS-PAGE. The CD11b is purified by proprietary chromatographic techniques.
Description: Leukocyte associated protein consists of two polypeptide chains with molecular weights 95 and 170kDa. The moleculae functions as a cell surface receptor for the C3bi complement fragment. It belongs to family of heterodimeric proteins (designated CD11) which share a common beta chain CD18 of 95kDa. The alpha chain component of the leukocyte associated antigen is expressed on granulocytes, monocytes and macrophages.
Source: Human
Host: Escherichia Coli.
Form: CD11b in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Physical Appearance: Sterile Filtered clear solution.
Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.
Gene Name: ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) [ Homo sapiens ]
Official Symbol: ITGAM
Synonyms: ITGAM; integrin, alpha M (complement component 3 receptor 3 subunit); CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; MGC117044; integrin alpha M; antigen CD11b (p170); macrophage antigen alpha polypeptide; neutrophil adherence receptor alpha-M subunit; CD11b; CD11 antigen-like family member B; CD11b antigen; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; integrin, alpha M (complement component 3 receptor 3 subunit); integrin, alpha M (complement component receptor 3, alpha; CD11b (p170), macrophage antigen alpha polypeptide); Integrin alpha-M
Gene ID: 3684
mRNA Refseq: NM_000632
Protein Refseq: NP_000623
MIM: 120980
UniProt ID: P11215
Chromosome Location: 16p11.2
Pathway: Cell adhesion molecules (CAMs); Hematopoietic cell lineage; Leukocyte transendothelial migration; Regulation of actin cytoskeleton
Function: calcium ion binding; glycoprotein binding; heparan sulfate proteoglycan binding; heparin binding; magnesium ion binding; opsonin binding; protein heterodimerization activity; receptor activity

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