Active Recombinant Human TGFB1

• Cat.No.: TGFB1-539H
• Product Overview: Human TGFB1 (P01137) full-elngth recombinant protein expressed in CHO cells.

Specification

• Species: Human
• Source: Human
• Tag: Non
• Description: Transforming growth factor beta 1 or TGF-μ1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. In humans, TGF-μ1 is encoded by the TGFB1 gene.
• Theoretical MW (kDa): 25
• Form: Lyophilized
• Preparation Method: Mammalian cell (CHO) expression system
• Purity: μ 98% by SDS-PAGE, μ 98% by HPLC
• Endotoxin Level: < 0.1 ng/ug
• Activity: The ED50 as determined by the ability of TGF-beta1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is < 0.05 ng/mL, corresponding to a specific activity of > 2 x 107 units/mg.
• Application: SDS-PAGE
• Storage Buffer: Lyophilized from sodium citrate, pH 3.5
• Storage: Store at -20°C on dry atmosphere.
• Unitprot ID: P01137

Gene Information

• Gene Name: TGFB1 transforming growth factor, beta 1 [ Homo sapiens ]
• Official Symbol: TGFB1
• Synonyms: TGFB1; transforming growth factor, beta 1; CED; LAP; DPD1; TGFB; TGFbeta; TGF-beta 1 protein; latency-associated peptide; Camurati-Engelmann disease; Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP
• Gene ID: 7040
• mRNA Refseq: NM_000660
• Protein Refseq: NP_000651
• MIM: 190180
• Chromosome Location: 19q13.1
• Pathway: Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway; Hemostasis; Influenza Infection; Signaling by TGF beta
• Function: growth factor activity; protein N-terminus binding; protein heterodimerization activity; protein homodimerization activity; transcription activator activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding