"TGFB1" Related Products


Recombinant Human TGFB1

Cat. No. : TGFB1-539H
Product Overview : Human TGFB1 (P01137) full-elngth recombinant protein expressed in CHO cells.
Description : Transforming growth factor beta 1 or TGF-μ1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. In humans, TGF-μ1 is encoded by the TGFB1 gene.
Theoretical MW (kDa) : 25
Form : Lyophilized
Preparation Method : Mammalian cell (CHO) expression system
Purity : μ 98% by SDS-PAGE, μ 98% by HPLC
Endotoxin Level : < 0.1 ng/ug
Activity : The ED50 as determined by the ability of TGF-beta1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is < 0.05 ng/mL, corresponding to a specific activity of > 2 x 107 units/mg.
Application : SDS-PAGE
Storage Buffer : Lyophilized from sodium citrate, pH 3.5
Storage : Store at -20°C on dry atmosphere.
Unitprot ID : P01137
Gene Name : TGFB1 transforming growth factor, beta 1 [ Homo sapiens ]
Official Symbol : TGFB1
Synonyms : TGFB1; transforming growth factor, beta 1; CED; LAP; DPD1; TGFB; TGFbeta; TGF-beta 1 protein; latency-associated peptide; Camurati-Engelmann disease; Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP
Gene ID : 7040
mRNA Refseq : NM_000660
Protein Refseq : NP_000651
MIM : 190180
Chromosome Location : 19q13.1
Pathway : Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway; Hemostasis; Influenza Infection; Signaling by TGF beta
Function : growth factor activity; protein N-terminus binding; protein heterodimerization activity; protein homodimerization activity; transcription activator activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding

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