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Native Human CTSG protein

Cat.No. : CTSG-1649H
Product Overview : Native Human CTSG was purified from Human Neutrophil.
Description : This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.
Source : Human Neutrophil
Species : Human
Form : Salt-free lyophilized solid.
Bio-activity : 2-4 units per mg protein
Molecular Mass : 23500
Purity : >=95% by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme that hydrolyzes one umole of Suc-Ala-Ala Pro-Phe-pNA (1 mM) per minute at 25 centigrade in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.
Storage : Stored at -20 centigrade
Gene Name : CTSG cathepsin G [ Homo sapiens ]
Official Symbol : CTSG
Synonyms : CTSG; cathepsin G; CG; CATG; MGC23078;
Gene ID : 1511
mRNA Refseq : NM_001911
Protein Refseq : NP_001902
MIM : 116830
UniProt ID : P08311
Chromosome Location : 14q12
Pathway : ACE Inhibitor Pathway, organism-specific biosystem; Activation of Matrix Metalloproteinases, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;
Function : heparin binding; peptidase activity; serine-type endopeptidase activity;

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