Recombinant Mouse Histone Deacetylase 5, GST-tagged

• Cat.No.: Hdac5-1593M
• Product Overview: Recombinant mouse Hdac5 (617-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 617-end a.a.
• Description: Hdac5 or Histone deacetylase 5 belongs to the class II histone deacetylase/acuc/apha family that possesses histone deacetylase activity and represses transcription when tethered to a promoter. Hdac5 plays a critical role in transcriptional regulation, cell cycle progression, and developmental events and also acts as a potential therapeutic target for the prevention of atherosclerosis.
• Applications: HDAC Assay; Western Blot
• Molecular Weight: 80 kDa
• Expression System: Sf9 insect cells using baculovirus
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >90%
• Concentration: 0.1 ug/ul
• Specific Activity: 110 RLU/min/ng
• Sequences: 617-end
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: Hdac5 histone deacetylase 5 [ Mus musculus ]
• Official Symbol: Hdac5
• Synonyms: Hdac5; histone deacetylase 5; Hdac4; mHDA1; AI426555; mKIAA0600; histone deacetylase 5; HD5; OTTMUSP00000002428; OTTMUSP00000030249; OTTMUSP00000030251; histone deacetylase 4; histone deacetylase mHDA1
• Gene ID: 15184
• mRNA Refseq: NM_001077696
• Protein Refseq: NP_001071164
• UniProt ID: Q6P9T4
• Chromosome Location: 11
• Function: histone deacetylase activity; hydrolase activity; protein binding; protein kinase C binding; repressing transcription factor binding; transcription corepressor activity; transcription factor binding